The neuroscience of cocaine : mechanisms and treatment / edited by Victor R. Preedy.

Format:

Book

Contributor:

Preedy, Victor R.

Language:

English

Subjects (All):

Cocaine--Physiological effect.

Cocaine.

Neuropharmacology.

Cocaine--pharmacology.

Cocaine-Related Disorders.

Neuropharmacology--methods.

Medical Subjects:

Cocaine--pharmacology.

Cocaine-Related Disorders.

Neuropharmacology--methods.

Genre:

Electronic books.

Physical Description:

1 online resource

Place of Publication:

London, United Kingdom : Academic Press, 2017.

System Details:

text file

Contents:

Front Cover; The Neuroscience of Cocaine; Copyright Page; Contents; List of Contributors; Preface; I. General Aspects, Features of Ill Health and Setting the Scene; 1 The Nervous System: A Starter Pack for Beginners; Summary Points; Key Facts; List of Abbreviations; 1.1 Introduction; 1.2 Development of the Brain; 1.3 The Parts of the Brain; 1.3.1 The Lateral Surface; 1.3.2 The Sagittal Surface; 1.3.3 The Cranial Nerves; 1.4 Cells of the Nervous System; 1.5 Sensory Systems of the Brain; 1.5.1 Somatosensory System ("Skin Sense"); 1.5.2 Proprioception ("Position Sense"); 1.5.3 Auditory System

1.5.4 Visual System1.5.5 Smell; 1.5.6 Taste; 1.6 More Complex Sensory Processing; 1.7 Cognitive Processing; 1.8 Motor Systems; 1.9 Higher Brain Functions; Mini-Dictionary of Terms; References; 2 Sex Differences in the Effects and Actions of Cocaine; Summary Points; Key Facts; List of Abbreviations; 2.1 Introduction; 2.2 Dopamine Signaling; 2.2.1 Sex Differences in Dopamine Signaling; 2.2.2 Estradiol's Effects on Dopamine Signaling; 2.3 Behavioral Effects of Cocaine; 2.3.1 Sex Differences in the Behavioral Response to Cocaine; 2.3.2 Estradiol's Effects on Behavior

2.4 Motivational Aspects of Cocaine Use2.4.1 Sex Differences in Motivation: Choice Paradigm; 2.4.2 Estradiol's Effects on Motivation; 2.5 Mechanisms of Addiction; 2.6 Sex Differences in Cocaine Use in Humans; 2.7 Summary; Mini-Dictionary of Terms; References; 3 Contribution of Stress to Cocaine Addiction; Summary Points; Key Facts; List of Abbreviations; 3.1 Introduction; 3.2 Clinical Evidence; 3.3 Preclinical Animal Studies; 3.4 Stress and Acquisition of Cocaine Self-Administration; 3.5 Stress and Escalation of Cocaine Self-Administration

3.6 Stress and Reinstatement of Extinguished Cocaine Seeking3.6.1 Stress-Triggered Relapse; 3.6.2 Stage-Setting Effects of Stress; 3.7 Effects of Cocaine Use on Stress Responses; 3.8 Genetics and Stress; 3.9 Sex Differences; 3.10 Treatment Implications; 3.11 Overview; Mini-Dictionary of Terms; References; 4 Strokes Associated With Cocaine Use; Summary Points; Key Facts; List of Abbreviations; 4.1 Introduction; 4.2 Epidemiology; 4.3 Clinical Features; 4.4 Pathophysiology; 4.4.1 Vasospasm; 4.4.2 Cocaine-Induced Platelet Activation; 4.4.3 Endothelial Dysfunction From Chronic Cocaine Use

4.4.4 Premature Atherogenesis Among Chronic Cocaine Users4.4.5 Cocaine-Induced Apoptosis of Cerebral Vascular Smooth Muscle Cells; 4.4.6 Vasculitis; 4.4.7 Cardiac Embolism; 4.4.8 Other Mechanisms; 4.5 Treatment; Mini-Dictionary of Terms; References; 5 Concentrations of Cocaine in Blood Samples From Impaired Drivers and Drug-Related Deaths; Summary Points; Key Facts; List of Abbreviations; 5.1 Introduction; 5.2 Disposition and Fate of Cocaine in the Body; 5.3 Absorption and Distribution; 5.4 Metabolism; 5.5 Excretion; 5.6 Determination of Cocaine in Biological Specimens

Notes:

Includes bibliographical references and index.

Print version record.

Other Format:

Print version:

ISBN:

9780128037928

012803792X

OCLC:

988286882

Access Restriction:

Restricted for use by site license.