Macrophages : Origin, Functions and Biointervention / edited by Malgorzata Kloc.

Format:

Book

Contributor:

Kloc, Malgorzata, editor.

SpringerLink (Online service)

Series:

Results and problems in cell differentiation 0080-1844 ; 62.

Results and Problems in Cell Differentiation, 0080-1844 ; 62

Language:

English

Subjects (All):

Medicine.

Cancer--Research.

Cancer.

Immunology.

Medical microbiology.

Developmental biology.

Biomedical materials.

Biomedicine.

Local Subjects:

Biomedicine.

Physical Description:

1 online resource.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2017.

System Details:

text file PDF

Summary:

This volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases. It also covers various aspects of macrophage development and formation, behavior and response to nano- and biomaterials, the latter of which have become very important components of modern medicine. Macrophages are evolutionarily conserved phagocytotic cells. In recent years macrophages have emerged as one of the most versatile cells of immune system, which, depending on the milieu and circumstance, participate in development or inhibition of cancer, regeneration, wound healing, inflammation, organ rejection and interaction between mother and a fetus. This book will be of particular interest to researchers working in immunology, cancer research, developmental biology, or related fields.

Contents:

Part A. Evolution, origin and fate of macrophages

1 Evolutionary aspects of Macrophages polarization

2 Development and functional differentiation of tissue-resident vs. monocyte-derived macrophages in inflammatory reactions

3 Hofbauer cells - placental macrophages of fetal origin

4 Mesenchymal stem cells direct the immunological fate of macrophages

5 Monocyte/Macrophage - NK cell Cooperation: Old Tools for New Functions

6 Macrophages in non-vertebrates: from insects and crustaceans to marine bivalves

Part B. Immunobiology of macrophages

7 F4/80 as a Major Macrophage Marker: The case of the Peritoneum and Spleen

8 Immunobiology of Nitric Oxide and Regulation of Inducible Nitric Oxide Synthase

9 Role for mechanotransduction in macrophage and dendritic cell immunobiology

Part C. Role of macrophages in disease

10 Macrophages' Role in Tissue Disease and Regeneration

11 Macrophages and their contribution to the development of atherosclerosis

12 Macrophage Dysfunction in Respiratory Disease

Part D. Macrophages as a target for biointervention

13 Activation of macrophages in response to biomaterials

14 Macrophage differentiation in normal and accelerated wound healing

15 Macrophages and RhoA pathway in transplanted organs. .

Other Format:

Printed edition:

ISBN:

9783319540900

Access Restriction:

Restricted for use by site license.