Adrenal Cortex: From Physiology to Disease

Format:

Book

Contributor:

Martinez, Antoine (Microbiologist), editor.

Val, Pierre, 1976- editor.

Series:

Frontiers Research Topics

Language:

English

Physical Description:

1 online resource (89 p.)

Other Title:

Adrenal Cortex

Place of Publication:

Frontiers Media SA 2016

Language Note:

English

Summary:

The adrenal gland plays essential roles in the control of body homeostasis, stress and immune responses. The adrenal cortex represents up to 90% of the gland and is specialised in the production of mineralocorticoids, glucocorticoids and adrenal androgens. This production is tightly coordinated and results from a unique zonal organisation. Although our knowledge of the molecular mechanisms controlling adrenal steroidogenesis is quite extensive, for decades, the mechanisms of adrenal cortex development, cellular homeostasis and renewal have remained elusive. The advent of new high-throughput technologies and sophisticated genetic approaches has brought tremendous progress in our understanding of how the adrenal cortex achieves and maintains its particular organisation. The aim of this Frontiers in Endocrinology Topic is to provide readers with a snapshot of our current knowledge on adrenal physiology and how deregulations of these processes result in adrenal diseases. This includes but is not limited to, basic research on adrenal development, cell lineage identification, progenitor cells, tissue renewal, control of differentiation and zonation and clinical research on the identification of disease-related genes.

Notes:

Creative Commons Attribution 4.0 International CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode

Description based on online resource ; title from PDF title page (viewed on 01/26/2021)

Access Restriction:

Open Access Unrestricted online access