Fast oscillations in cortical circuits / Roger D. Traub, John G.R. Jefferys, and Miles A. Whittington.

Format:

Book

Author/Creator:

Traub, Roger D., author.

Jefferys, John G. R., author.

Whittington, Miles A., author.

Series:

Computational neuroscience

Language:

English

Subjects (All):

Cerebral cortex.

Hippocampus (Brain).

Neural circuitry.

Oscillations.

Physical Description:

1 online resource (xviii, 324 pages) : illustrations.

Other Title:

MIT Press CogNet.

Place of Publication:

Cambridge, Massachusetts : The MIT Press, [1999]

System Details:

text file

Summary:

The study of cortical oscillations is of great interest to those working in many areas of neuroscience. A fast coherent EEG rhythm called gamma or "40 Hz" has been implicated in cognition, as it may play a role in binding together features of objects. This rhythm may also be important for consciousness, as a number of drugs that induce general anesthesia disrupt the synchronization of the rhythm at clinically relevant concentrations. There is also suggestive evidence implicating dysfunction of gamma rhythms in Alzheimer's disease, and perhaps in other neuropsychiatric disorders.

In Fast Oscillations in Cortical Circuits, the authors use a combination of electrophysiological and computer modeling techniques to analyze how large networks of neurons can produce both epileptic seizures and functionally relevant synchronized oscillations. Specific topics covered include single hippocampal pyramid cells, hippocampal interneurons, synaptic interactions, gamma oscillations in brain slices as well as in vivo, the mechanisms of oscillation-synchronization (both local and long-range), the switch from gamma to beta frequencies and its implications for memory, and the significance of gamma oscillations for brain function.

Contents:

Chapter 1. Oscillations: What They Are, What They Might Be Good For 1

Chapter 2. Single Hippocampal Pyramidal Cells 7

Chapter 3. Single Hippocampal Interneurons 35

Chapter 4. Synaptic Interactions in the Hippocampus 47

Chapter 5. Networks of Pyramidal Cells: Synchronized Bursts 73

Chapter 6. Networks of Interneurons I: Synchronized Bursts 103

Chapter 7. Gamma Oscillations in Vivo 113

Chapter 8. Networks of Interneurons II: Gamma Oscillations in Vitro 153

Chapter 9. Gamma Oscillations in Networks of Interneurons and Pyramidal Cells in Vitro I: Mechanisms of Synchronization 185

Chapter 10. Gamma Oscillations in Networks of Interneurons and Pyramidal Cells in Vitro II: Synaptic Plasticity and the Switch to Beta Frequencies 237

Chapter 11. Conclusions: Are Gamma Oscillations Significant for Brain Function? 267.

Notes:

"Bradford book."

Includes bibliographical references (pages 273-316) and index.

Description based on print version record.

Other Format:

Print version: Traub, Roger D. Fast oscillations in cortical circuits.

ISBN:

9780262285148

0262285142

Access Restriction:

Restricted for use by site license.