Vascular biology of the placenta / Yuping Wang.

Format:

Book

Author/Creator:

Wang, Yuping, MD, author.

Series:

Colloquium digital library of life sciences

Colloquium series on integrated systems physiology ; # 75.

Colloquium series on integrated systems physiology ; 75

Language:

English

Subjects (All):

Placenta--Blood-vessels.

Placenta.

Placenta--blood supply.

Medical Subjects:

Placenta--blood supply.

Genre:

Electronic books.

Physical Description:

1 online resource (ix, 113 pages) : illustrations.

Edition:

Second edition.

Place of Publication:

[San Rafael, California] : Morgan & Claypool, 2017.

System Details:

Mode of access: World Wide Web.

System requirements: Adobe Acrobat reader.

text file

Summary:

The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.

Contents:

1. Introduction

2. Placental blood circulation

2.1 Maternal-placental blood circulation

2.2 Fetal-placental circulation

3. Structure of the placenta

4. Cell types of the placenta

4.1 Cytotrophoblasts and syncytiotrophoblasts

4.2 Villous core stroma cells

4.3 Pericytes

4.4 Vascular endothelial cells

5. Oxygen tension and placental vascular development

5.1 Oxygen tension and establishment of maternal-placental circulation

5.2 Hypoxia and trophoblast differentiation

5.3 Models of placental hypoxia

6. Vasculogenesis and angiogenesis of human placenta

7. Angiogenic factors

7.1 Vascular endothelial growth factor family molecules and vascular endothelial growth factor receptors

7.2 FGFs and FGF receptors

7.3 Angiopoietins and tie system

8. Vasoactivators and placental vasoactivity

8.1 Renin-angiotensin system

8.2 Arachidonic acid metabolites: thromboxane and prostacyclin

8.3 Endothelin-1 and its receptors

8.4 Nitric oxide

8.5 Chymase

8.6 Role of trophoblasts in regulation of placental vasoactivity

9. Trophoblast-derived extracellular vesicles

10. Placenta-derived micrornas and immune response in pregnancy

11. Lymphatic phenotypic characteristics of the human placenta

12. Placental tissue and cord blood stem cells

13. Summary

Acknowledgments

References

Author biography.

Notes:

Part of: Colloquium digital library of life sciences.

Includes bibliographical references (pages 89-112).

Title from PDF title page (viewed on June 27, 2017).

Other Format:

Print version:

ISBN:

9781615047512

OCLC:

991875232

Access Restriction:

Restricted for use by site license.