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Bioinformatics : Volume II: Structure, Function, and Applications / edited by Jonathan M. Keith.

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Holman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
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Format:
Book
Contributor:
Keith, Jonathan M., editor.
SpringerLink (Online service)
Series:
Methods in molecular biology 1064-3745 ; 1526.
Methods in Molecular Biology, 1064-3745 ; 1526
Language:
English
Subjects (All):
Life sciences.
Bioinformatics.
Physical Description:
1 online resource (XI, 426 pages) : 88 illustrations, 26 illustrations in color.
Edition:
Second edition 2017.
Contained In:
Springer eBooks
Place of Publication:
New York, NY : Springer New York : Imprint: Humana Press, 2017.
System Details:
text file PDF
Summary:
This second edition provides updated and expanded chapters covering a broad sampling of useful and current methods in the rapidly developing and expanding field of bioinformatics. Bioinformatics, Volume II: Structure, Function, and Applications, Second Edition is comprised of three sections: Structure, Function, Pathways and Networks; Applications; and Computational Methods. The first section examines methodologies for understanding biological molecules as systems of interacting elements. The Applications section covers numerous applications of bioinformatics, focusing on analysis of genome-wide association data, computational diagnostic, and drug discovery. The final section describes four broadly applicable computational methods that are important to this field. These are: modeling and inference, clustering, parameterized algorithmics, and visualization. As a volume in the highly successful Methods in Molecular Biology series, chapters feature the kind of detail and expert implementation advice to ensure positive results. Comprehensive and practical, Bioinformatics, Volume II: Structure, Function, and Applications is an essential resource for graduate students, early career researchers, and others who are in the process of integrating new bioinformatics methods into their research. .
Contents:
3D Computational Modeling of Proteins Using Sparse Paramagnetic NMR Data
Inferring Function from Homology
Inferring Functional Relationships from Conservation of Gene Order
Structural and Functional Annotation of Long Non-Coding RNAs
Construction of Functional Gene Networks Using Phylogenetic Profiles
Inferring Genome-Wide Interaction Networks
Integrating Heterogeneous Datasets for Cancer Module Identification
Metabolic Pathway Mining
Analysis of Genome-Wide Association Data
Adjusting for Familial Relatedness in the Analysis of GWAS Data
Analysis of Quantitative Trait Loci
High-Dimensional Profiling for Computational Diagnosis
Molecular Similarity Concepts for Informatics Applications
Compound Data Mining for Drug Discovery
Studying Antibody Repertoires with Next-Generation Sequencing
Using the QAPgrid Visualization Approach for Biomarker Identification of Cell-Specific Transcriptomic Signatures
Computer-Aided Breast Cancer Diagnosis with Optimal Feature Sets: Reduction Rules and Optimization Techniques
Inference Method for Developing Mathematical Models of Cell Signaling Pathways Using Proteomic Datasets
Clustering
Parameterized Algorithmics for Finding Exact Solutions of NP-Hard Biological Problems
Information Visualization for Biological Data.
Other Format:
Printed edition:
ISBN:
9781493966134
Access Restriction:
Restricted for use by site license.

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