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Immunotherapy and Biomarkers in Neurodegenerative Disorders / edited by Martin Ingelsson, Lars Lannfelt.

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Format:
Book
Contributor:
Ingelsson, Martin, editor.
Lannfelt, Lars, editor.
SpringerLink (Online service)
Series:
Methods in pharmacology and toxicology 1557-2153
Methods in Pharmacology and Toxicology, 1557-2153
Language:
English
Subjects (All):
Medicine.
Pharmacology.
Physical Description:
1 online resource (X, 289 pages) : 40 illustrations, 32 illustrations in color.
Contained In:
Springer eBooks
Place of Publication:
New York, NY : Springer New York : Imprint: Humana Press, 2016.
System Details:
text file PDF
Summary:
This practical volume examines a number of topics that explore the current status of immunotherapy and diagnostic markers for neurodegenerative disorders. With a focus on Alzheimer's disease, the first sections of the book examine immunotherapeutic approaches for the aforementioned disease as well as for Parkinson's disease and Huntington's disease, amongst others. The last section of the book covers the importance of biomarker techniques to catch these diseases early enough for the treatments to be most useful. Written for the Methods in Pharmacology and Toxicology series, this book contains the kind of detailed descriptions and implementation advice that will offer a smooth transition into the lab. Authoritative and useful, Immunotherapy and Biomarkers in Neurodegenerative Disorders aims to aid in the continued progress in the development of novel immune-based drugs and diagnostic tools for these devastating brain diseases.
Contents:
Immunotherapy Against Amyloid-β in Alzheimer's Disease: An Overview
Active Immunization Against the Amyloid-β Peptide
Immunotherapy Against N-Truncated Amyloid-β Oligomers
Immunotherapy Against Amyloid-β Protofibrils: Opportunities and Challenges
Immunotherapy Against α-Synuclein Pathology
Extracellular α-Synuclein as a Target for Immunotherapy
Immunotherapy of Parkinson's Disease
Tau Immunotherapy
Active and Passive Immunotherapy Against Tau: Effects and Potential Mechanisms
Immunotherapy on Experimental Models for Huntington's Disease
Cerebrospinal Fluid Biomarkers in Alzheimer's Disease
Volumetric MRI as a Diagnostic Tool in Alzheimer's Disease
PET Imaging as a Diagnostic Tool in Alzheimer ́s Disease
Αlpha-Synuclein as a Diagnostic Biomarker for Parkinson's Disease
Imaging as a Diagnostic Tool in Parkinson's Disease
Mass Spectrometry-Based Proteomics in Biomarker Discovery for Neurodegenerative Diseases.
Other Format:
Printed edition:
ISBN:
9781493935604
Access Restriction:
Restricted for use by site license.

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