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The Gene Ontology Handbook / edited by Christophe Dessimoz, Nives Škunca.

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Holman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
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Format:
Book
Contributor:
Dessimoz, Christophe, editor.
Škunca, Nives, editor.
SpringerLink (Online service)
Series:
Methods in molecular biology 1064-3745 ; 1446.
Methods in Molecular Biology, 1064-3745 ; 1446
Language:
English
Subjects (All):
Life sciences.
Bioinformatics.
Physical Description:
1 online resource (XII, 305 pages) : 56 illustrations, 50 illustrations in color.
Contained In:
Springer eBooks
Place of Publication:
New York, NY : Springer New York : Imprint: Humana Press, 2017.
System Details:
text file PDF
Summary:
This book is open access under a CC BY 4.0 license. This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system.
Contents:
Primer on Ontologies
The Gene Ontology and the Meaning of Biological Function
Primer on the Gene Ontology
Best Practices in Manual Annotation with the Gene Ontology
Computational Methods for Annotation Transfers from Sequence
Text Mining to Support Gene Ontology Curation and Vice Versa
How Does the Scientific Community Contribute to Gene Ontology?
Evaluating Computational Gene Ontology Annotations
Evaluating Functional Annotations of Enzymes Using the Gene Ontology
Community-Based Evaluation of Computational Function Prediction
Get GO!: Retrieving GO Data Using AmiGO, QuickGO, API, Files, and Tools
Semantic Similarity in the Gene Ontology
Gene-Category Analysis
Gene Ontology: Pitfalls, Biases, and Remedies
Visualizing GO Annotations
A Gene Ontology Tutorial in Python
Annotation Extensions
The Evidence and Conclusion Ontology (ECO): Supporting GO Annotations
Complementary Sources of Protein Functional Information: The Far Side of GO
Integrating Bio-Ontologies and Controlled Clinical Terminologies: From Base Pairs to Bedside Phenotypes
The Vision and Challenges of the Gene Ontology.
Other Format:
Printed edition:
ISBN:
9781493937431
Access Restriction:
Restricted for use by site license.

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