Gene-environment interplay / edited by Maria B. Sokolowski, Stephen F. Goodwin.

Format:

Book

Contributor:

Sokolowski, Maria B., editor.

Goodwin, Stephen F., editor.

Series:

Advances in genetics ; 0065-2660 77 (CKB)954926956852 (DLC)47030313

Advances in genetics ; v. 77, 0065-2660

Language:

English

Subjects (All):

Genetics.

Genotype-environment interaction.

Physical Description:

1 online resource (145 p.)

Edition:

1st ed.

Place of Publication:

San Diego, Calif : Academic Press, 2012.

Language Note:

English

Summary:

The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in knowledge gained from genetics reasearch. This thematic volume of Advances in Genetics looks at Socio-Genetics.* Includes methods for testing with ethical, legal, and social implications* Critically analyzes future

Contents:

CHAPTER 1: SOCIAL INFLUENCES ON CIRCADIAN RHYTHMS AND SLEEP IN INSECTS

I. Introduction

II. The Circadian System of Insects

III. Social Influences on Circadian Rhythms in Insects

A. Social synchronization

B. Social influences on the ontogeny of circadian rhythms

C. Social modulation of plasticity in the expression of circadian rhythms

D. Additional social influences on circadian rhythms

IV. Sleep

A. Sleep in invertebrates

B. Sleep in honey bees with and without circadian rhythms

V. Social Influences on Sleep in Insects

VI. Conclusions

References

CHAPTER 2: INTERPLAY BETWEEN SOCIAL EXPERIENCES AND THE GENOME: EPIGENETIC CONSEQUENCES FOR BEHAVIOR

I. Epigenetic Mechanisms and Development

A. DNA methylation

B. Histone modifications

C. MicroRNA

D. Interaction between epigenetic pathways

II. Epigenetic Impact of Social Experiences

A. Epigenetic effects of mother-infant interactions

1. Variation in maternal care

2. Maternal separation

3. Maternal abuse

4. Enhancing mother-infant interactions

5. Human studies of the epigenetic impact of childhood adversity

B. Adult social stress

III. Role of Epigenetics in Shaping Social Behavior

A. Epigenetic dysregulation and social behavior

B. Sexual differentiation

IV. Conclusions and Future Directions

CHAPTER 3: ONE, TWO, AND MANY-A PERSPECTIVE ON WHAT GROUPS OF DROSOPHILA MELANOGASTER CAN TELL US ABOUT SOCIAL DYNAMICS

A. Caveat

II. The Behavioral Effects of Social Context

A. Social learning and memory

B. Social synchronizing of activity and rest

C. Aggression

D. Mating, paternity, and offspring

III. System-Level and Network Approaches to Social Context

IV. Conclusion

CHAPTER 4: THE CIRCADIAN CLOCK OF THE FLY: A NEUROGENETICS JOURNEY THROUGH TIME

II. The Molecular Components of the Clock

A. The first loop (part I): PER and TIM accumulation results in the late night/early morning repression of the ``evening tran

B. The second loop (part I): VRI and PDP1 time the expression of the ``morning transcripts ́ ́

C. The second loop (part II): an imperfect picture

D. The first loop (part II): controversial regulators of evening genes

E. Posttranscriptional regulation

1. mRNA stability

2. Control of translation

F. Posttranslational regulation of clock proteins (part I): PER and TIM1. DOUBLE-TIME and NEMO

2. CASEIN KINASE 2 and SHAGGY

3. Protein phosphatases

4. SLIMB and CTRIP

G. Posttranslational regulation of clock proteins (part II): CLK

III. Entrainment

A. Anatomy of the clock

B. Entrainment to light

C. Entrainment to temperature

IV. Which Clock Is It Anyway?

V. Conclusions

Index. Color Plate.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-283-58416-6

9786613896612

0-12-387697-4

OCLC:

811491805