Advances in clinical chemistry. Volume 49 / edited by Gregory S. Makowski.

Format:

Book

Contributor:

Makowski, Gregory S.

Series:

Advances in Clinical Chemistry

Advances in clinical chemistry, 0065-2423 ; v. 49

Language:

English

Subjects (All):

Clinical chemistry.

Physical Description:

1 online resource (203 p.)

Place of Publication:

Amsterdam : Elsevier, 2009.

Language Note:

English

Summary:

Volume 49 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical exploration to cutting-edge microarray technology. * Leading experts from academia and clinical laboratory science * Volume emphasizes novel laboratory advances with application to clinical laboratory diagnostics and practical basic science studies

Contents:

Front Cover; Advances in Clinical Chemistry; Copyright Page; Contents; Contributors; Preface; Chapter 1: High-Sensitivity Troponin: A New Tool for Pathophysiological Investigation and Clinical Practice; 2. Background and Aim; 3. Introduction: Troponin Framework Within Myocardial Cells and Release Kinetics After Myocardial Damage; 4. Impact of the New Definition of Myocardial Infarction on Laboratory Practice and Instrumentation: The Need for High-Sensitivity cTnI and cTnT Methods; 5. The Impact of High-Sensitivity cTnI and cTnT Methods on Clinical Practice

6. High-Sensitivity cTnI and cTnT Methods: A Powerful Tool for Monitoring Physiological Renewal and Pathological Remodeling of the Myocardial Tissue?7. Use of High-Sensitivity cTnI and cTnT Methods in a Multimarker Approach for Early Screening: An Increase in Diagnostic and Prognostic Efficiency?; 8. Conclusion; References; Chapter 2: Biochemical Biomarkers of Oxidative Collagen Damage; 2. The Collagen Family: Structure and Biochemistry; 3. Chemical Nature and Reactivity of Oxygen; 4. In Vivo Production of RNOS; 5. RNOS Biological Activity; 6. In Vivo Markers of Oxidant Stress

7. Oxidant-Induced Changes in Collagens8. Biomarkers of Collagen Oxidative Damage; 9. Critical Comments and Concluding Remarks; References; Chapter 3: Biochemical Basis of Fabry Disease with Emphasis on Mitochondrial Function and Protein Trafficking; 2. Introduction; 3. Inheritance; 4. Clinical Picture; 5. Diagnosis; 6. Treatment; 7. Biochemical Basis; References; Chapter 4: Urinary Biomarkers for the Detection of Renal Injury; 2. Introduction; 3. Biomarker Development for Kidney Diseases; 4. Biomarkers for AKI; 5. Biomarker Development and Implementation; 6. Summary; References

Chapter 5: Biomarkers of Bone and Mineral Metabolism Following Bone Marrow Transplantation2. Introduction; 3. Clinical Features of BMT-Related Bone Loss; 4. Changes in Bone-Turnover Markers After BMT; 5. Calcium, Parathyroid Hormone (PTH), and Vitamin D; 6. Sex Hormones; 7. RANKL and Osteoprotegerin; 8. Cytokines and Growth Factors; 9. Conclusion; References; Chapter 6: Factor V Leiden and Activated Protein C Resistance; 2. Introduction; 3. The Protein C System; 4. APC Resistance and FV Leiden; 5. Conclusions and Perspectives; Acknowledgement; References

Chapter 7: Self-Assembled Tethered Bimolecular Lipid Membranes2. Introduction; 3. Assembly of tBLMs from Telechelics and Reconstitution of Proteins; 4. The Peptide-Tethered Lipid Bilayer Membrane (peptBLM); 5. Protein-Tethered Bilayer Lipid Membrane (protBLM); 6. Conclusions; Acknowledgments; References; Index; Color Plates

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-283-02026-2

9786613020260

0-08-095100-7

OCLC:

707918246