International review of cell and molecular biology. Volume two eighty-eight / edited by Kwang W. Jeon.

Format:

• Book

Contributor:

• Jeon, Kwang W.

Series:

• International review of cell and molecular biology ; 288

Language:

English

Subjects (All):

• Cytology.
• Molecular biology.

Physical Description:

1 online resource (278 p.)

Place of Publication:

San Diego, CA : Academic, 2011.

Language Note:

English

Summary:

International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2009: 6.088. * Authored by some of the foremost scientists in the field * Provides up-to-date information and directions for future research * Valuable reference material for advanced undergraduates, graduate students and professional sc

Contents:

• Front Cover; International Review of Cell and Molecular Biology; Copyright; Contents; Contributors; Chapter 1: The Membrane Receptor for Plasma Retinol-Binding Protein, A New Type of Cell-Surface Receptor; 1. Introduction; 2. Diverse Physiological Functions of Vitamin A, a Molecule Essential for Vertebrate Survival; 3. Retinol-Binding Protein, the Specific Carrier of Vitamin A in Blood; 4. Diverse Evidence for the Existence of an RBP Receptor that Mediates Vitamin A Uptake; 5. Identification of RBP Receptor; 6. Structure and Function Analysis of the RBP Receptor's Interaction with RBP
• 7. Pertinent Questions Related to RBP Receptor8. RBP Receptor as a Potential Target in Treating Human Diseases; 9. Concluding Remarks; Acknowledgments; References; Chapter 2: Vascular Smooth-Muscle-Cell Activation...; 1. Introduction; 2. Characteristics of Vascular Smooth-Muscle Cells; 3. Proteomics Approaches for VSMC Proteome Mapping; 4. Posttranslational Modifications and Their Biological Functions in VSMCs; 5. From Putative Markers to New Therapeutic Targets; 6. Concluding Remarks; Acknowledgments; References
• Chapter 3: Molecular Basis for Endothelial Lumen Formation and Tubulogenesis During Vasculogenesis and Angiogenic Sprouting1. Introduction; 2. Overview of Endothelial Lumen Formation and Tubulogenesis; 3. Molecular Mechanisms Controlling Vascular Lumen Formation; 4. Functional Roles of Cdc42 and Rac1 in EC Lumen and Tube Formation; 5. Roles of MT1-MMP and Vascular Guidance Tunnels in EC Lumen Formation and Tube Remodeling Events; 6. Mechanisms Controlling EC Lumen and Tube Stability; 7. Role for MMPs in the Molecular Control of Vascular Tube Regression Responses
• 8. Conclusions and Future DirectionsAcknowledgments; References; Chapter 4: SUMO and Its Role in Human Diseases; 1. Introduction; 2. The Sumoylation Cycle; 3. Sumoylation and Cancer; 4. Sumoylation of Proteins Involved in Neurodegenerative Diseases; 5. Sumoylation and Heart Disease; 6. Concluding Remarks; Acknowledgments; References; Chapter 5: Focal Adhesion Kinase...; 1. Introduction; 2. Biological and Physiological Significance of FAK; 3. Domain Structure; 4. Autoinhibition; 5. FAK Binding Partners; 6. Development of FAK Therapeutics; 7. Future Directions; References
• Chapter 6: Roles of Small Ubiquitin-Related Modifiers in Male Reproductive Function1. Introduction; 2. Regulation of Protein Functions by Sumoylation: Lessons from Other Cell Types; 3. Unique Aspects of Sumoylation in Male Germ Cells; 4. Concluding Remarks and Future Perspectives; Acknowledgments; References; Index

Notes:

• Description based upon print version of record.
• Includes bibliographical references and index.

ISBN:

• 1-283-52640-9
• 9786613838858
• 0-12-386042-3

OCLC:

721194419