International review of cell and molecular biology. Volume 293 / edited by Kwang W. Jeon.

Format:

Book

Contributor:

Jeon, Kwang W.

Language:

English

Subjects (All):

Cells.

Molecular biology.

Physical Description:

1 online resource (328 p.)

Edition:

1st ed.

Place of Publication:

Amsterdam : Elsevier/Academic Press, 2012.

Language Note:

English

Summary:

International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2009: 6.088. * Authored by some of the foremost scientists in the field * Provides up-to-date information and directions for future research * Valuable reference material for advanced undergraduates, graduate students and professional sc

Contents:

Front cover; International Review of Cell and Molecular Biology; Copyright; Contents; Contributors; Chapter one: Defective Trafficking of Rhodopsin and Its Role in Retinal Degenerations; 1. Introduction; 2. Retinitis Pigmentosa: The Most Common Inherited Retinal Degeneration; 2.1. Degeneration and retinitis pigmentosa: An apoptotic function; 2.2. Different types of retinitis pigmentosa; 2.2.1. Syndromic retinitis pigmentosa; 2.2.1.1. Usher syndrome; 2.2.1.2. Bardet-Biedl syndrome; 2.2.2. Nonsyndromic retinitis pigmentosa; 2.2.2.1. Autosomal recessive retinitis pigmentosa

2.2.2.1.1. Leber's congenital amaurosis2.2.2.2. Autosomal dominant retinitis pigmentosa; 2.2.2.3. Mitochondrial, X-linked, and diallelic retinitis pigmentosas; 3. Rhodopsin: Function and History; 3.1. What is known about rhodopsin to date?; 3.1.1. Biochemical characteristics, spectral properties, and role in vision; 3.1.2. Protein-protein interactions: The trafficking of rhodopsin; 3.2. Do all mutants cause equal degeneration? A classification system for rhodopsin mutants; 4. Future Directions and Emerging Treatments; 5. Concluding Remarks; References

Chapter two: Adherens Junction Assembly and Function in the Drosophila Embryo1. Introduction; 2. AJ Components; 2.1. DE-cad/shotgun; 2.2. Armadillo; 2.3. a-Catenin; 2.4. p120-catenin; 2.5. Others; 3. AJ Assembly and Maintenance; 3.1. Assembling spot AJs at cellularization; 3.2. Assembling belt-like AJs (zonulae adherentes) at gastrulation; 3.3. Maintaining AJs; 4. AJ Regulation and Function; 4.1. Internalizing the mesoderm by tissue invagination (the ventral furrow); 4.2. Converting to mesenchyme and back again (EMT and MET)

4.3. Elongating the body axis through convergent extension (the germband)4.4. Flattening an epithelium by rotary cell elongation (the amnioserosa); 4.5. Maintaining boundaries between epithelial tissues; 4.6. Internalizing and forming the tracheal system; 4.7. Internalizing and forming the salivary glands; 4.8. Internalizing the nervous system (neuroblast delamination/ingression); 4.9. Epithelial cell division; 4.10. Epithelial structure and apoptosis; 4.11. Enclosing the embryo with ectoderm (dorsal closure); 5. Concluding Remarks; Acknowledgments; References

Chapter three: New Insights into the Regulation of Myosin Light Chain Phosphorylation in Retinal Pigment Epithelial Cells1. Introduction; 2. Retinal Pigment Epithelium; 2.1. Structure; 2.2. Function; 2.3. RPE involvement in eye diseases; 3. Actin Cytoskeleton; 3.1. Actin structure and polymerization; 3.2. Signaling to the actin cytoskeleton and force generation; 3.2.1. Rho family of GTPases; 3.2.2. Contractile stress fibers; 3.3. Actin cytoskeleton in polarized RPE cells; 4. Myosin Superfamily of Molecular Motors; 4.1. General structure and classification

4.2. Myosin II in muscle and non-muscle cells

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-283-43418-0

9786613434180

0-12-394640-9

OCLC:

775872708