Advances in virus research. Volume 80 / edited by Karl Maramorosch, Aaron J. Shatkin, Frederick A. Murphy.

Format:

Book

Contributor:

Maramorosch, Karl.

Shatkin, Aaron J.

Murphy, Frederick A.

Series:

Advances in virus research ; v. 80.

Advances in virus research, 0065-3527 ; v. 80

Language:

English

Subjects (All):

Virology--Research.

Virology.

Physical Description:

1 online resource (144 p.)

Edition:

1st ed.

Place of Publication:

London : Academic Press, an imprint of Elsevier, 2011.

Language Note:

English

Summary:

Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology. The impact factor for 2009 is 5.522 placing it 2nd in the highly competitive category of virology. * Contributions from leading authorities * Informs and updates on all the latest developments in the field

Contents:

Front Cover; Virus Research; Copyright; Contents; Contributors; Chapter 1: Mechanistic Intersections Between Picornavirus Translation and RNA Replication; Background; IRES-Dependent Translation and IRES-Transacting Factors; Viral Modification of Canonical and Noncanonical Translation Factors; Important Aspects of RNA Replication; Important RNA Elements in RNA Replication; Viral and Cellular Proteins Involved in RNA Replication; Alteration of Host Cell Environment and Implications for Replication; The Switch from Viral Translation to Viral RNA Replication; Acknowledgments; References

Chapter 2: Mycoviruses, RNA Silencing, and Viral RNA RecombinationIntroduction; Overcoming Technical Challenges to Mycovirus Research; Antiviral Defense Mechanisms in Fungi; Regulation of the Fungal Antiviral RNA Silencing Response; RNA Silencing Contributes to Mycovirus RNA Recombination; Concluding Remarks; References; Chapter 3: Viruses and Metabolism: Alterations of Glucose and Glutamine Metabolism Mediated by Human Cytomegalovirus; The Warburg Effect and Cancer Cells; Human Cytomegalovirus; Glucose, Pyruvate, and Glutamine Metabolism in HCMV-Infected Cells

How does HCMV Accomplish These Alterations in Glucose and Glutamine Metabolism so that Glucose can be Used for Fatty AcidConclusions and Discussion; References; Chapter 4: Regulatory Roles of Protein Kinases in Cytomegalovirus Replication; Introduction; The Nature of Herpesviral Protein Kinases; CrossTalk Between Herpesviral and Cellular Protein Kinases; Conclusions; Outlook for antiviral research; Acknowledgments; References; Chapter 5: HIV Immune Evasion: Disruption of Antigen Presentation by the HIV Nef Protein; Introduction to HIV-1 Pathogenesis; HIV-1 Nef

Candidate Host Factors that Partner with NefDownmodulation of MHC-I: Endocytic Mechanism; Downmodulation of MHC-I: Evidence for Targeting of Newly Synthesized Protein in the Secretory Pathway; Summary; Acknowledgments; References; Index; Colour Plate

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-283-17389-1

9786613173898

0-12-385988-3

OCLC:

746746894