Advances in parasitology. Volume 65 / edited by R. Muller, D. Rollinson, S.I. Hay.

Format:

Book

Contributor:

Hay, S. I. (Simon I.)

Muller, R.

Rollinson, D.

Series:

Advances in parasitology ; v. 65.

Advances in parasitology ; v. 65

Language:

English

Subjects (All):

Molecular parasitology.

Parasitology.

Physical Description:

1 online resource (373 p.)

Edition:

1st ed.

Place of Publication:

Boston ; Amsterdam : Elsevier/Academic Press, 2007.

Language Note:

English

Summary:

First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Advances in Parasitology includes medical studies on parasites of major influence, such as Plasmodium falciparum and Trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. Eclectic volumes are supplemented by thematic volumes on various topics including Remote Sensing and Geographical Information Systems

Contents:

Front Cover; Advances in Parasitology; Copyright Page; Contents; Contributors; Preface; Chapter 1: ABO Blood Group Phenotypes and Plasmodium falciparum Malaria: Unlocking a Pivotal Mechanism; 1. Introduction; 2. Methods; 2.1. Inclusion Criteria; 2.2. Data analysis; 3. The Nature of ABO Histo-Blood Antigens; 4. ABO Phenotypes and Malaria Risk; 4.1. Population genetics; 4.2. Infection risk; 4.3. Severe malaria; 4.4. Placental malaria; 5. Biological Basis for ABO Phenotype-Related Susceptibility to Malaria; 5.1. Affinity for Anopheles gambiae; 5.2. Shared antigens; 5.3. Inflammatory response

5.4. Invasion of RBCs5.5. Rosetting; 5.6. Cytoadherence; 6. Conclusions and Research Implications; Acknowledgements; References; Chapter 2: Structure and Content of the Entamoeba histolytica Genome; 1. Introduction; 2. Genome Structure; 2.1. The E. histolytica genome sequencing, assembly and annotation process; 2.2. Karyotype and chromosome structure; 2.3. Ribosomal RNA genes; 2.4. tRNA genes; 2.5. LINEs; 2.6. SINEs; 2.7. Other repeats; 2.8. Gene number; 2.9. Gene structure; 2.10. Gene size; 2.11. Protein domain content; 2.12. Translation-related proteins; 2.13. Analysis of cell cycle genes

2.14. Transcription3. Virulence Factors; 3.1. Gal/GalNAc lectin; 3.2. Cysteine endopeptidases; 3.3. Amoeba pores and related proteins; 3.4. Antioxidants; 4. Metabolism; 4.1. Energy metabolism; 4.2. Amino acid catabolism; 4.3. Polyamine metabolism; 4.4. Biosynthesis of amino acids; 4.5. Lipid metabolism; 4.6. Coenzyme A biosynthesis and pantothenate metabolism; 4.7. Nucleic acid metabolism; 4.8. Missing pieces; 4.9. Transporters; 5. The Cytoskeleton; 5.1. Actin and microfilaments; 5.2. Tubulins and microtubules; 5.3. Molecular motors; 6. Vesicular Traffic

6.1. Complexity of vesicle trafficking6.2. Proteins involved in vesicle formation; 6.3. Proteins involved in vesicle fusion; 6.4. Comparisons and implications; 6.5. Glycosylation and protein folding; 7. Proteins Involved in Signalling; 7.1. Phosphatases; 7.2. Kinases; 7.3. Calcium binding proteins; 8. The Mitosome; 9. Encystation; 9.1. Chitin synthases; 9.2. Chitin deacetylases; 9.3. Chitinases; 9.4. Jacob lectins; 9.5. Gal/GalNAc lectins; 9.6. Summary and comparisons; 10. Evidence of Lateral Gene Transfer in the E. histolyticaGenome; 10.1. How do the 96 LGT cases stand up?

10.2. Where do the genes come from?10.3. What kinds of gene are being transferred?; 11. Microarray Analysis; 12. Future Prospects for the E. histolyticaGenome; Acknowledgements; References; Chapter 3: Epidemiological Modelling for Monitoring and Evaluation of Lymphatic Filariasis Control; 1. Introduction; 2. Why Monitor and Evaluate Filariasis Control Programmes; 3. Mathematical Models and the Design of Monitoring and Evaluation Plans; 3.1. Three roles of mathematical models in parasite monitoring programmes; 4. Models and Quantifying Intervention Endpoint Targets

4.1. Parasite elimination endpoints: Vector biting thresholds and worm break points

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-281-18905-7

9786611189051

0-08-055682-5

OCLC:

476128408