Advances in genetics. Volume 55 / edited by Jeffrey C. Hall ... [et al.].

Format:

Book

Contributor:

Hall, Jeffrey C.

Series:

Advances in genetics ; v. 55.

Advances in genetics ; v. 55

Language:

English

Subjects (All):

Genetics.

Heredity.

Physical Description:

1 online resource (199 p.)

Place of Publication:

Boston ; Amsteram : Elsevier, c2005.

Language Note:

English

Summary:

The field of genetics is rapidly evolving and new medical breakthroughs are occurring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.

Contents:

Front Cover; Advances in Genetics; Copyright Page; Contents; Contributors; Chapter 1. Site-Specific DNA Recombinases as Instruments for Genomic Surgery; I. Introduction; II. Inadequacy of Current Methods; III. Site-Specific Recombination; IV. Mechanisms of Site-Specific Recombination; V. Transposition; VI. Applied Site-Specific Recombination and Transposition Systems; VII. Changing Recombination Site Specificity; VIII. Mutagenesis-Selection Strategies; IX. Structure-Based Strategies. Z-Resolvases; X. Targeting Transposition to Specific Sequences

XI. General Considerations in Applications of Site-Specific Recombinases and TransposasesXII. Prospects and Conclusions; References; Chapter 2. Human Clinical Trials of Plasmid DNA Vaccines; I. Background; II. Development of DNA Vaccines for Clinical Trials; III. Human Clinical Trials; IV. Limitations of DNA Vaccine Potency; V. Prospects and Conclusion; References; Chapter 3. Genetic and Environmental Influences on Antisocial Behaviors. Evidence from; I. Appraising the Quantitative Behavioral-Genetic Evidence Base; II. Estimating the Relative Influences of Genes and Environments

III. Do the Omnibus Estimates of Genetic and Environmental Influences Always Apply, or do These Influences Vary Under Different Conditions?IV. Testing Developmental Theory of Antisocial Behavior; V. Testing Hypotheses About Environmental Causation; VI. Testing the Hypothesis of Interaction Between Genes and Environments; VII. The Way Forward; References; Chapter 4. Genetics of Graviperception in Animals; I. Introduction; II. Vertebrate Genetic Models; III. The Arthropod Genetic Model; IV. The Nematode Model System; V. Conclusion; References

Chapter 5. Retroviral DNA Integration-Mechanism and ConsequencesI. Introduction; II. Retroviral Life Cycle; III. Mechanism of Integration; IV. Integrase Structure; V. Composition of Integrase Complexes In Vivo; VI. Retroviral Integration Targeting; VII. Consequences of Integration into Host Chromosomes; VIII. Conclusions; References; Index; Color Plate Section

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-281-02035-4

9786611020354

0-08-052233-5

OCLC:

476072979