Advances in cancer research. Volume 90 / edited by George F. Vande Woude, George Klein.

Format:

Book

Contributor:

Vande Woude, George F.

Klein, George.

Series:

Advances in cancer research ; 90

Language:

English

Subjects (All):

Cancer--Research.

Cancer.

Oncology.

Physical Description:

1 online resource (254 p.)

Place of Publication:

New York : Academic Press, 2003.

Language Note:

English

Summary:

The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics.The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics.

Contents:

Front Cover; Advances in Cancer Research; Copyright Page; Contents; Contributors to Volume 90; Chapter 1. Microenvironmental Regulation of the Initiated Cell; I. Introduction; II. Initiation and Promotion of Tumor Development in the Skin of Animals Painted with Carcinogens; III. Inhibition of Initiated Keratinocytes in Culture by Normal Keratinocytes; IV. Inhibition of Neoplastic Progression in Mice or in Organotypic Culture by Normal Keratinocytes; V. Inhibition of Virally Transformed Malignant Keratinocytes by Dermal Fibroblasts in Skin Grafts and in Subcutaneous Injections

VI. Restriction of Mutant Keratinocytes to the Epidermal Proliferative Unit in Ultraviolet (UV) Carcinogenesis of the SkinVII. Microenvironmental Suppression of Neoplastic Transformation Among Cultured Fibroblasts; VIII. Evaluation of the Evidence Concerning a Role for Proteases in Tumor Initiation; IX. Visualization of Microenvironmental Regulation in Spontaneous Transformation of Mouse Fibroblasts; X. Microenvironmental Effects on Mammary Neoplasia; XI. Further Developments on the Role of Proteases in Carcinogenesis; XII. Conclusions; References

Chapter 2. Persistent Infection with Helicobacter Pylori and the Development of Gastric CancerI. Introduction-H. Pylori and Cancer Development; II. Bacterial Colonization and Persistence; III. H. Pylori-Mediated Mucosal Inflammation; IV. Effects of H. Pylori Infection on Epithelial Cell Turnover; V. H. Pylori-Mediated Promotion of Tumor Development; VI. Host Susceptibility Genes and Gastric Cancer Associated with H. Pylori Infection; VII. Concluding Remarks; References

Chapter 3. High-Resolution Analysis of Genetic Events in Cancer Cells Using Bacterial Artificial Chromosome Arrays and Comparative Genome HybridizationI. Introduction; II. Evolution of Molecular Cytogenetics; III. Development of BAC Resources; IV. CGHa in the Analysis of Cancer; V. Summary; References; Chapter 4. Natural Killer Cells and Cancer; I. Introduction; II. NK Cell Biology; III. NK Cell Effector Functions; IV. Receptors Turning NK Cells ''On'' and ''Off''; V. NK Cells in Tumor Immunosurveillance; VI. Tumor Escape Mechanisms; VII. Conclusion; References

Chapter 5. Immunity to Cancer Through Immune Recognition of Altered Self: Studies with MelanomaI. Introduction; II. Melanoma Antigens; III. Cellular Responses to Differentiation Antigens; IV. Antibody-Mediated Tumor Immunity and Autoimmunity; V. Clinical Applications; References; Chapter 6. Chemical Carcinogens as Foreign Bodies and Some Pitfalls Regarding Cancer Immune Surveillance; I. Introduction; II. Chemical Carcinogenesis; III. Increased Tumor Incidence by MCA in IFNyR-KO Compared with IFNyR-WT Mice

IV. No New Evidence that Supports T-Cell-Mediated Immune Surveillance of MCA-Induced or Spontaneous Tumors

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

9786611004590

9781281004598

1281004596

9780080490212

0080490212

OCLC:

476058707