Advances in immunology. Volume 84 / edited by Frederick W. Alt.

Format:

Book

Contributor:

Taliaferro, William H. (William Hay), 1895-1973.

Humphrey, John, 1915-1987.

Series:

Advances in Immunology

Language:

English

Subjects (All):

Immunology.

Microbiology.

Physical Description:

1 online resource (295 p.)

Place of Publication:

New York : Academic Press, 2004.

Language Note:

English

Summary:

Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.* Interactions between NK Cells and B Lymphocytes* Multitasking of helix-loop-helix proteins in lymphopoiesis* The pathogenesis of Diabetes in the NOD

Contents:

Front Cover; Advances in Immunology; Copyright Page; Contents; Contributors; Chapter 1. Interactions Between NK Cells and B Lymphocytes; I. Introduction; II. B Lymphocytes; III. NK Cells; IV. NK-B-Cell Interactions In Vitro; V. In Vivo NK-B Cell Interactions; VI. The Role of NK-B-Cell Interactions in Autoimmune Diseases; VII. NK-B-Cell Interactions during Infections; VIII. Conclusions; References; Chapter 2. Multitasking of Helix-Loop-Helix Proteins in Lymphopoiesis; I. Introduction; II. HLH Proteins and B-Cell Development; III. HLH Proteins and T-Cell Development

IV. HLH Protein and Notch SignalingV. HLH Proteins and Leukemia; VI. Conclusions; References; Chapter 3. Customized Antigens for Desensitizing Allergic Patients; I. Introduction; II. Allergy Diagnosis and Immunotherapy: From Extracts to Allergen Arrays and Engineered Vaccines; III. Novel Antigen Preparations to Improve SIT; IV. Customized Allergen DNA Vaccines; V. Short Overview of Alternative Treatments and Supporting Adjuvants for SIT; VI. Summary and Conclusions; References; Chapter 4. Immune Response Against Dying Tumor Cells; I. Introduction

II. Minimal Elements of the Antitumor Immune ResponseIII. Subroutines of Cell Death: Apoptosis and Necrosis; IV. In Vivo Immunogenicity of Apoptotic Versus Necrotic Tumor Cells; V. Apoptosis. A Tolerogenic Type of Tumor Cell Death?; VI. Strategies to Enhance the Immunogenicity of Dying Tumor Cells; VII. Concluding Remarks; References; Chapter 5. HMGB1 in the Immunology of Sepsis (Not Septic Shock) and Arthritis; I. Introduction; II. Modern Clinical Syndromes: Septic Shock is not Severe Sepsis; III. TNF is a Mediator of Septic Shock Syndrome, but Not Severe Sepsis Syndrome

IV. HMGB1 and Anti-HMGB1 in Severe Sepsis, Not Septic ShockV. Biochemistry and Molecular Biology of HMGB1; VI. HMGB1 Signaling via RAGE and TLR2; VII. Cytokine Activities of HMGB1; VIII. HMGB1 in Arthritis; IX. Perspective and Future; References; Chapter 6. Selection of the T-Cell Repertoire: Receptor-Controlled Checkpoints in T-Cell Development; I. Thymic Selection. A Historical Perspective; II. Early T-Cell Development; III. Late T-Cell Development; IV. The Role of Thymic Selection in Recessive and Dominant Mechanisms of Self-Tolerance; V. Concluding Remarks; References

Chapter 7. The Pathogenesis of Diabetes in the NOD MouseI. Introduction; II. Origin of the NOD Mouse; III. Pathogenesis of Diabetes in the NOD Mouse; IV. Leukocytes Involved in the Pathogenesis of Diabetes in the NOD Mouse; V. Other Autoimmune Diseases Associated with the NOD Mouse; VI. Breakthough Moments in the Study of the Pathogenesis of Diabetes in the NOD Mouse; VII. Concluding Remarks; References; Index; Contents of Recent Volumes; Color Plate Section

Notes:

Description based upon print version of record.

ISBN:

9786611004804

9781281004802

1281004804

9780080490342

0080490344

OCLC:

476058800