Advances in pharmacology. Volume 2 / edited by Silvio Garattini, Parkhurst A. Shore.

Format:

Book

Contributor:

Garattini, Silvio.

Shore, Parkhurst A.

Series:

Advances in pharmacology ; v. 2

Language:

English

Subjects (All):

Pharmacology.

Chemotherapy.

Physical Description:

1 online resource (401 p.)

Place of Publication:

New York : Academic Press, 1963.

Language Note:

English

Summary:

ADVANCES IN PHARMACOLOGY VOL 2

Contents:

Cover; Contents; Contributors; Chapter 1. Experimental and Clinical Aspects of Drug Toxicity; I. Introduction; II. Drug Toxicity in Humans; III. Methods; IV. Drug-Unrelated Factors Affecting the Outcome of Animal Toxicity Experiments; V. Drug-Related Factors Affecting the Outcome of Animal Toxicity Experiments; VI. Clinical Toxicity in Man and Animal Experiments; VII. Economics of the Experimental Safety Evaluation Program; VIII. Conclusions; References; Chapter 2. Pharmacological Considerations in the Treatment of Myasthenia Gravis; I. Introduction

II. Clinical Features and Natural History of Myasthenia GravisIII. Pathology; IV. On the Pathophysiology and Pathogenesis of Myasthenia Gravis; V. Diagnosis of Myasthenia Gravis; Pharmacological Tests; VI. Drug Therapy and Specific Drug Actions in Myasthenia Gravis; VII. Summary; References; Chapter 3. Potentialities for and Present Status of Pharmacological Research in Genetically Controlled Mice; I. Introduction; II. Genetic Control of Quality; III. Pharmacogenetics; IV. Added Comments; References; Chapter 4. Hormones and Atherosclerosis; I. Introduction

II. Modification of Atheroscleroais in Relation to Endocrine GlandsIII. Chemical and Metabolic Studies; IV. Final Comments; References; Chapter 5. Nitrogen Mustards and Related Alkylating Agents; I. Introduction; II. Trends in Synthesis; III. Fundamental Biochemistry and Biology; IV. Use in Clinical Practice; V. Conclusion; References; Chapter 6. Purine and Pyrimidine Antimetabolites in Cancer Chemotherapy; I. Introduction; II. Selective Toxicity and Cancer Chemotherapy; III. Metabolism; IV. Mechanisms of Action; V. Resistance

VI. Application of Laboratory Findings to Human Cancer ChemotherapyVII. Is There Any Basis for Optimism?; References; Author Index; Index

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-281-46652-2

9786611466527

0-08-058092-0

OCLC:

808683971