Advances in immunology. Volume 81 / edited by Frederick W. Alt.

Format:

Book

Contributor:

Taliaferro, William H. (William Hay), 1895-1973.

Humphrey, John, 1915-1987.

Series:

Advances in immunology ; 81.

Advances in immunology ; 81

Language:

English

Subjects (All):

Immunology.

Microbiology.

Physical Description:

1 online resource (411 p.)

Place of Publication:

New York : Academic Press, 2003.

Language Note:

English

Summary:

Volume 81 of Advances in Immunology contains articles on a vast range of immunology topics including the regulation of the immune response by the interaction of chemokines and proteases as well as roles of the Semaphorin Family in immune regulation. It has a chapter devoted to B Lymphoid Neoplasms of Mice and another on the Zebrafish as a model organism to study development of the immune system. This volume will be of interest to immunologists in all industries.* Edited by a new editor, Frederick W. Alt* Covers molecular mechanisms of host-pathogen interaction* Discusses

Contents:

Front Cover; Advances in Immunology; Copyright Page; Contents; Contributors; Foreword; Chapter 1. Regulation of the Immune Response by the Interaction of Chemokines and Proteases; I. Introduction to Chemokines; II. Posttranslational Modification of CXC Chemokines; III. CC Chemokines as Protease Substrates; IV. The CD26-Chemokine Connection; References; Chapter 2. Molecular Mechanisms of Host-Pathogen Interaction: Entry and Survival of Mycobacteria in Macrophages; I. Introduction; II. Innate Recognition of Pathogens; III. Phagocytosis and Intracellular Trafficking in Macrophages

IV. Intracellular Survival of Bacterial PathogensV. Mycobacterial Infection; VI. Conclusions; References; Chapter 3. B Lymphoid Neoplasms of Mice: Characteristics of Naturally Occurring and Engineered Diseases and Relationships to Human Disorders; I. Introduction; II. Classification of Mouse B Cell-lineage Lymphomas; III. Pathogenesis of Spontaneous B Cell-lineage Neoplasms; IV. Conclusions; References; Chapter 4. Prions and the Immune System: A Journey Through Gut, Spleen, and Nerves; I. Prion Biology: Some Basic Facts; II. Peripheral Entry Sites of Prions: Complicity of Immune Cells

III. Lymphocytes and Prion PathogenesisIV. Prion Hideouts in Lymphoid Organs; V. A Spleen is not a Lymph Node: Idiosyncrasies in the Lymphotropism of Prions; VI. Sympathetic Nerves: A Neuroimmune Link?; VII. Innate Immunity and Antiprion Defense; VIII. Adaptive Immunity and Pre-Exposure Prophylaxis Against Prions; IX. The Prion Doppelganger; X. Prion Immunology: Quo Vadis?; XI. An Essential Glossary of Prion Jargon; References; Chapter 5. Roles of the Semaphorin Family in Immune Regulation; I. Overview; II. Class IV Semaphorin (1): CD100/Sema4D; III. Class IV Semaphorin (2): Sema4A

IV. Virus-Encoded Semaphorins and their Cellular CounterpartsV. Class III Semaphorin: Sema3A in Immune Cell Migration; VI. Neuropilin-1 in initial T cell/DC Contacts; VII. Perspectives; References; Chapter 6. HLA-G Molecules: from Maternal-Fetal Tolerance to Tissue Acceptance; I. Introduction; II. The HLA-G Gene and Polymorphism; III. Regulation of HLA-G Gene Expression; IV. Processing and Transport of HLA-G Molecules; V. Structural and Functional Properties of HLA-G Molecules; VI. Role of HLA-G in Normal and Pathological Pregnancies; VII. HLA-G in Organ Transplantation

VIII. HLA-G in MalignanciesReferences; Chapter 7. The Zebrafish as a Model Organism to Study Development of the Immune System; I. Introduction; II. Innate Immunity of Teleosts; III. Ontogeny of Adaptive Immunity from Fishes to Mammals; IV. Phenotypic Characterization of Zebrafish Hematolymphoid Cells; V. The Zebrafish as a Vertebrate Model System for Forward Genetic Screens; VI. Zebrafish Screens for Lymphoid Mutants; VII. Reverse Genetic Approaches; VIII. Gene Expression Screens; IX. Use of Genomics: Getting Started with the Zebrafish; X. Concluding Remarks: Impact of Zebrafish on Immunology

References

Notes:

Description based upon print version of record.

ISBN:

9786611118839

9781281118837

1281118834

9780080548302

008054830X

OCLC:

808625468