Advances in immunology. Volume 99 / edited by Frederick W. Alt.

Format:

Book

Contributor:

Alt, Frederick W.

Series:

Advances in immunology ; v. 99.

Advances in immunology ; v. 99

Language:

English

Subjects (All):

Immunology.

Allergy.

Physical Description:

1 online resource (241 p.)

Place of Publication:

Amsterdam : Elsevier ; New York : Academic Press, c2008.

Language Note:

English

Summary:

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Contents:

Front Cover; Advances in Immunology; Copyright Page; Contents; Contributors; Chapter 1: Cis-Regulatory Elements and Epigenetic Changes Control Genomic Rearrangements of the IgH Locus; 1. Introduction; 4. Class Switch Recombination and Somatic Hypermutation; Chapter 2: DNA-PK: The Means to Justify the Ends?; 1. Introduction; 2. Composition; 3. DNA Binding and Kinase Activation; 10. End Processing to Promote End Conservation; References; Chapter 3: Thymic Microenvironments for T-Cell Repertoire Formation; 2. Trafficking of Developing Thymocytes; 3. Cortical Microenvironment; Acknowledgments

Chapter 4: Pathogenesis of Myocarditis and Dilated Cardiomyopathy2. The Evidence for an Autoimmune Process in Myocarditis; 3. Mouse Models of Myocarditis; 4. Role of Proinflammatory Cytokines in Myocarditis; 5. Role of T Helper Cells in Myocarditis; 7. Conclusions/Directions for Future Research; Acknowledgments; References; Chapter 5: Emergence of the Th17 Pathway and Its Role in Host Defense; 1. Introduction; 3. Functions of the Th17-Derived Cytokines; 4. IL-23/IL-17-Mediated Innate Immunity; 5. Th17 Cells and Innate Immunity

7. IL-23/IL-17-Mediated Responses in Specific Microbial Infections8. Closing Remarks; Chapter 6: Peptides Presented In Vivo by HLA-DR in Thyroid Autoimmunity; 3. Natural Ligands for HLA Class II in Autoimmune Thyroid Tissue; Acknowledgments; References; Subject Index; Contents of Recent Volumes; Color Plates

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

9786612286506

9781282286504

1282286501

9780080921723

0080921728

OCLC:

808726497