Methods in nano cell biology / edited by Bhanu P. Jena.

Format:

Book

Contributor:

Jena, Bhanu P.

Series:

Methods in cell biology ; v. 90.

Methods in cell biology, 0091679X ; v. 90

Language:

English

Subjects (All):

Ultrastructure (Biology).

Imaging systems in biology.

Physical Description:

1 online resource (534 p.)

Place of Publication:

Amsterdam ; Boston : Academic Press : Elsevier, c2008.

Language Note:

English

Summary:

Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Nanobiology focuses on the properties and structure of complex assemblies of biomolecules-biochips and molecular motors, for example-in conjunction with distinctive surfaces, rods, dots, and materials of nanoscience. Nano Cell Biology will describe the current applications of nanobiology to the study of the structure, function, and metabolic processes of cells.Key Features*Provides historical background on this newly emerging field*Covers th

Contents:

Front Cover; Methods in Cell Biology; Copyright Page; Dedication Page; Contents; Contributors; Preface; Chapter 1: Extracellular Dynamics at nm Resolution in Live Cells; I. Introduction; II. Materials and Methods; III. Conclusion; Acknowledgments; References; Chapter 2: Intracellular Organelle Dynamics at nm Resolution; I. Introduction; II. Materials and Methods; III. Discussion; Acknowledgments; References; Chapter 3: Atomic Force Microscopy as a Tool to Study the Proteasome Assemblies; I. Introduction; II. Rationale; III. Methods; IV. Discussion; V. Summary; Acknowledgment; References

Chapter 4: Biomineralization at the Nanoscale: Learning from DiatomsI. Introduction to Nanotechnology; II. Introduction to Diatoms; III. Investigating Diatom Mesoscale Silica Formation; IV. Nanoscale Imaging of Living Diatoms; V. Nanoscale Elasticity Measurements; VI. Examination of Diatom Valves; VII. Examination of Diatom Girdle Bands; VIII. Examination of Diatom Setae; IX. Future Directions; Acknowledgments; References; Chapter 5: Quantitative Phase Imaging of Nanoscale Cell Structure and Dynamics; I. Introduction and Rationale; II. Methods; III. Applications of QPI

IV. Summary and OutlookAcknowledgments; References; Chapter 6: Fourier Imaging Correlation Spectroscopy for Cellular Structure-Function; I. Introduction and Background; II. Theoretical Descriptions of FICS; III. FICS Optical Layout; IV. Examples of FICS Applications; V. Conclusions; Acknowledgments; References; Chapter 7: Nanobiology of the Primary Cilium-Paradigm of a Multifunctional Nanomachine Complex; I. Introduction; II. Self-Assembly; III. Ciliogenesis; IV. Elucidating the Functional Role of Primary Cilia; V. The Medical Consequences of Aciliogenesis-A Veritable Pandora's Box

VI. Concluding RemarksReferences; Chapter 8: Assembly and Disassembly of SNAREs in Membrane Fusion; I. Introduction; II. Materials and Methods; III. Discussion; Acknowledgment; References; Chapter 9: Understanding Membrane F usion: Combining Experimental and Simulation Studies; I. Introduction; II. Materials and Methods; III. Discussion; Acknowledgments; References; Chapter 10: Structure and Dynamics of Metalloproteins in Live Cells; I. Introduction; II. Rationale; III. Methods; IV. Materials; V. Discussion; VI. Summary; Acknowledgments; References

Chapter 11: Light-Activated Ion Channels for Remote Control of Neural ActivityI. Introduction; II. Discussion; III. Methods; IV. Conclusion; Acknowledgments; References; Chapter 12: Molecular Modeling and Simulation Studies of Ion Channel Structures, Dynamics and Mechanisms; I. Introduction; II. Homology-Based Structure Prediction of Transmembrane Proteins; III. PB Profiles for the Energetics of an Ion in a Channel; IV. MD Simulations; V. Free Energy Methods; VI. Summary; References

Chapter 13: Nano-Scale Imaging and Dynamics of Amylin-Membrane Interactions and Its Implication in Type II Diabetes Mellitus

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

9786612287152

9781282287150

128228715X

9780080949109

008094910X

OCLC:

808778017