Fragment-based drug design : tools, practical approaches, and examples / edited by Lawrence C. Kuo.

Format:

Book

Contributor:

Kuo, Lawrence C.

Series:

Methods in enzymology ; v. 493.

Methods in enzymology, 0076-6879 ; v. 493

Language:

English

Subjects (All):

Drug development.

Drugs--Design.

Drugs.

Physical Description:

1 online resource (661 p.)

Edition:

1st ed.

Place of Publication:

San Diego, Calif. : Academic Press, an imprint of Elsevier, 2011.

Language Note:

English

Summary:

There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, s

Contents:

section 1. Tools

section 2. Practical approaches

section 3. Examples.

Notes:

Description based upon print version of record.

Includes bibliographical references and indexes.

ISBN:

9786613164001

9781283164009

1283164000

9780123812759

0123812755

OCLC:

742333641