Fermentation and biochemical engineering handbook : principles, process design, and equipment / edited by Henry C. Vogel and Celeste L. Todaro.

Format:

Book

Contributor:

Vogel, Henry C., editor.

Todaro, Celeste L., editor.

Language:

English

Subjects (All):

Biochemical engineering--Handbooks, manuals, etc.

Biochemical engineering.

Fermentation--Handbooks, manuals, etc.

Fermentation.

Physical Description:

1 online resource (455 p.)

Edition:

Third edition.

Place of Publication:

Waltham, Massachusetts ; Oxford, England : William Andrew, 2014.

Language Note:

English

Summary:

A complete reference for fermentation engineers engaged in commercial chemical and pharmaceutical production, Fermentation and Biochemical Engineering Handbook emphasizes the operation, development and design of manufacturing processes that use fermentation, separation and purification techniques. Contributing authors from companies such as Merck, Eli Lilly, Amgen and Bristol-Myers Squibb highlight the practical aspects of the processes-data collection, scale-up parameters, equipment selection, troubleshooting, and more. They also provide relevant perspectives for the different indus

Contents:

Front Cover; Fermentation and Biochemical Engineering Handbook; Copyright Page; Contents; Preface to the Third Edition; Preface to the Second Edition; Preface to the First Edition; In Memory of Henry C. Vogel; List of Contributors; I: Fermentation; 1 Fermentation Pilot Plant; Prologue; 1.0 Microbial Fermentation; 1.1 Fermentation Pilot Plant; 1.2 Bioreactors and Culture Techniques for Microbial Processes; 1.3 Application of Computer Control and Sensing Technologies for Fermentation Process; 1.4 Scale-Up; 1.5 Bioreactors for Recombinant DNA Technology; Further reading

2 Mammalian Cell Culture System1.0 Introduction; 2.0 Culture Media; 3.0 Microcarrier Culture and General Control Parameters; 4.0 Perfusion Culture Systems as a New High Density Culture Technology; 5.0 Sedimentation Column Perfusion Systems; 6.0 High Density Culture Using a Perfusion Culture System with Sedimentation Column; Acknowledgment; References and Bibliography (Section 2); Further Reading; 3 Bioreactors for Plant Cell Tissue and Organ Cultures; 1.0 Background of the Technique-Historical Overview; 2.0 Media Formulations; 3.0 General Applications; 4.0 Bioreactors-Hardware Configuration

5.0 Bioreactor Size6.0 Culture Period; 7.0 Aeration and Agitation; 8.0 Microbial Contamination; 9.0 Characteristics; 10.0 Manipulation; 11.0 Scale-up Problems; 12.0 Bioprocess Measurement and Control; References (Section 3); Further Reading; 4 Nutritional Requirements in Fermentation Processes; 1.0 Introduction; 2.0 Nutritional Requirements of the Cell; 3.0 The Carbon Source; 4.0 The Nitrogen and Sulfur Source; 5.0 The Source of Trace and Essential Elements; 6.0 The Vitamin Source and Other Growth Factors; 7.0 Physical and Ionic Requirements; 8.0 Media Development

9.0 Effect of Nutrient Concentration on Growth RateReferences; Further Reading; 5 Fermentation for Biofuels and Bio-Based Chemicals; 1.0 Introduction, History, and Theory; 1.1 The Biofuel and Bio-Based Chemical Industries Originated with Natural Fermentation Products; 1.2 Theory: Principles of Chemistry and Biology Guide the Selection of Fermentation Products, Substrates, and Organisms; 1.2.1 One Example of the Way that One Organism's Metabolic Pathways Enable it to Process a Variety of Substrates into a Sel...

1.3 Historical Foundation of Biofuel- and Bio-Based Chemical Fermentation Industries1.3.1 Table of Biofuel- and Bio-Based Chemical Production Processes in Operation at Commercial Scale, 1910 through 2013; 2.0 Fermentation Organism Development for a Biofuel- or Bio-Based Chemical Product; 2.1 Native Strain Screening, Selection, and Genetic Modification; 2.2 Adaption to the Fermentation Background and Lowest Cost Nutrient Mix, to Overcome Inhibition and Minimize Operating Costs; 3.0 Biofuel- or Bio-Based Chemical Fermentation Process Development and Design; 4.0 Practical Applications

4.1 Selection

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on online resource; title from PDF title page (ebrary, viewed April 10, 2014).

ISBN:

9781455730469

1455730467

OCLC:

875820594