Computational pharmaceutics : application of molecular modeling in drug delivery / edited by Defang Ouyang and Sean C. Smith.

Format:

Book

Contributor:

Ouyang, Defang, editor.

Smith, Sean C., editor.

Series:

Advances in pharmaceutical technology.

Advances in Pharmaceutical Technology

Language:

English

Subjects (All):

Drug delivery systems.

Computational biology.

Drugs--Design.

Drugs.

Physical Description:

1 online resource (336 p.)

Place of Publication:

Chichester, [England] : Wiley, 2015.

Language Note:

English

Summary:

Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening. Now these techniques are used to model or mimic the behavior of molecules, and help us study formulation at the molecular level. Computational pharmaceutics enables us to understand the mechanism of drug delivery, and to develop new drug delivery systems. The book discusses the modeling of different drug delivery systems, including cyclodextrins, solid dispersions, polymorphism prediction, dendrimer-based delivery systems, surfactant-based micelle, poly

Contents:

Introduction of computational pharmaceutics / Ouyang

Crystal energy landscapes for aiding crystal form selection / Sarah Price

Solubilization of poor-soluble drugs in cyclodextron formulation / Ouyang

Molecular modeling for polymeric and micellar drug delivery / Sharon M.Loverde

Solid dispersion : a pragmatic method to improve the bioavailability of poorly soluble drugs / Ouyang

Computer simulations of lipid membranes and liposomes for drug delivery / Becky Notman

Molecular modeling for protein aggregation and formulation / Jim Warwicker

Computational simulation of drug delivery by nano-materials at molecular level / Youyong Li

Molecular and analytical modeling of nanodiamond for drug delivery applications / Amanda Barnard

Molecular modeling of LDH drug delivery systems / Vinuthaa Murthy

Molecular dynamics simulation as a tool to study the efficacy of PEGylation / Alex Bunker

Synchrotron radiation micro computed tomography : a new approach for quantitative 3D structural architecture of drug delivery systems / Jiwen Zhang

Pharmacokinetic modelling and simulation in drug delivery / Raj.

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

1-118-57397-8

1-118-57398-6

OCLC:

900159092