Drug delivery strategies for poorly water-soluble drugs / edited by Dennis Douroumis and Alfred Fahr.

Format:

Book

Contributor:

Douroumis, Dennis.

Fahr, Alfred.

Series:

Advances in Pharmaceutical Technology

Advances in pharmaceutical technology

Language:

English

Subjects (All):

Drug delivery systems.

Pharmaceutical chemistry.

Drug carriers (Pharmacy).

Solubility.

Physical Description:

1 online resource (644 p.)

Edition:

1st ed.

Place of Publication:

Chichester, West Sussex : John Wiley & Sons, 2012.

Language Note:

English

Summary:

Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. Consequently, the development oftechniques and materials to overcome these hurdles is a major area of research in pharmaceutical companies. Drug Delivery Strategies for Poorly Water-Soluble Drugs provides a comprehensive overview of currently used formulation strategies for hydrophobic drugs, including liposome formulation, cyclodextrin drug carriers, solid lipid nanoparticles, polymeric drug encapsulation delivery syst

Contents:

Self-assembled delivery vehicles for poorly water-soluble drugs : basic theoretical considerations and modeling concepts / Silvio May and Alfred Fahr

Liposome as intravenous solubilizers for poorly water soluble drugs / Peter van Hoogevest, Mathew Leigh and Alfred Fahr

Drug solubilization and stabilization of cyclodextrin drug carriers / Thorsteinn Loftsson and Marcus Eli Brewster

Solid lipid nanoparticles for drug delivery / Sonja Joseph and Heike Bunjes

Polymeric drug delivery systems for encapsulating hydrophobic drugs / Naveed Ahmed, C.E. Mora-Heurtas, Chiraz Jaafar-Maalej, Hatem Fessi and Abdelhamid Elaissari

Polymeric drug delivery systems for encapsulating hydrophobic drugs / Dagmar Fischer

Development of self-emulsifying drug delivery systems (SEDDS) for oral ioavailability enhancement of poorly soluble drugs / Dimitrios G. Fatouros and Anette Müllertz

Novel top-down technologies : effective production of ultra-fine drug nanocrystals / Cornelia.M. Keck, S. Kobierski, R. Mauludin and Rainer H. Müller

Nanosuspensions with enhanced drug dissolution rates of poorly water-soluble drugs / Dennis Douroumis

Microemulsions for drug solubilization and delivery / X.Q. Wang and Qiang Zhang

Enhancing drug solubility and bioavailability using hot melt extruded solid dispersions / Shu Li, David S. Jones and Gavin P. Andrews

Penetration enhancers, solvents and the skin / Jonathan Hadgraft and Majella E. Lane

Dendrimers for enhanced drug solubilization / Narendra K. Jain and Rakesh K. Tekade

Polymeric micelles for the delivery of poorly soluble drugs / Swati Biswas, Onkar S.Vaze, Sara Movassaghian and Vladimir P. Torchilin

Nanostructured silicon-based materials as a drug delivery system for water insoluble drugs / Vesa-Pekka Lehto, Jarno Salonen, Helder Santos and Joakim Riikonen

Micro- and nanosizing of poorly soluble drugs by grinding techniques / Stefan Scheler

Enhanced solubility of poorly soluble drugs via spray drying / Cordin Arpagaus, David Rütti and Marco Meuri.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on metadata supplied by the publisher and other sources.

ISBN:

9781118444726

1118444728

9781299252707

1299252702

9781118444771

1118444779

9781118444672

1118444671

OCLC:

809845200