Mass spectrometry : instrumentation, interpretation, and applications / edited by Rolf Ekman ... [et al.].

Format:

Book

Contributor:

Ekman, Rolf, 1938-

Series:

Wiley-Interscience series on mass spectrometry.

Wiley-Interscience series on mass spectrometry

Language:

English

Subjects (All):

Mass spectrometry.

Physical Description:

1 online resource (407 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, N.J. : John Wiley & Sons, c2009.

Language Note:

English

Summary:

With contributions from noted experts from Europe and North America, Mass Spectrometry Instrumentation, Interpretation, and Applications serves as a forum to introduce students to the whole world of mass spectrometry and to the many different perspectives that each scientific field brings to its use. The book emphasizes the use of this important analytical technique in many different fields, including applications for organic and inorganic chemistry, forensic science, biotechnology, and many other areas. After describing the history of mass spectrometry, the book moves on to discuss ins

Contents:

MASS SPECTROMETRY; CONTENTS; FOREWORD; CONTRIBUTORS; PART I INSTRUMENTATION; 1 DEFINITIONS AND EXPLANATIONS; References; 2 A MASS SPECTROMETER'S BUILDING BLOCKS; 2.1. Ion Sources; 2.1.1. Gas Discharge; 2.1.2. Thermal Ionization; 2.1.3. Spark Source; 2.1.4. Glow Discharge; 2.1.5. Inductively Coupled Plasma; 2.1.6. Electron Ionization; 2.1.7. Chemical Ionization; 2.1.8. Atmospheric Pressure Chemical Ionization; 2.1.9. Photoionization; 2.1.10. Multiphoton Ionization; 2.1.11. Atmospheric Pressure Photoionization; 2.1.12. Field Ionization; 2.1.13. Field Desorption; 2.1.14. Thermospray Ionization

2.1.15. Electrospray Ionization 2.1.16. Desorption Electrospray Ionization; 2.1.17. Direct Analysis in Real Time; 2.1.18. Secondary Ion Mass Spectrometry; 2.1.19. Fast Atom Bombardment; 2.1.20. Plasma Desorption; 2.1.21. Laser Desorption/Ionization; 2.1.22. Matrix-Assisted Laser Desorption/Ionization; 2.1.23. Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionization; 2.2. Mass Analyzers; 2.2.1. Time-of-Flight; 2.2.2. Magnetic/Electric Sector; 2.2.3. Quadrupole Mass Filter; 2.2.4. Quadrupole Ion Trap; 2.2.5. Orbitrap; 2.2.6. Fourier Transform Ion Cyclotron Resonance

2.2.7. Accelerator Mass Spectrometry 2.3. Detectors; 2.3.1. Photoplate Detector; 2.3.2. Faraday Detector; 2.3.3. Electron Multipliers; 2.3.4. Focal Plane Detector; 2.3.5. Scintillation Detector; 2.3.6. Cryogenic Detector; 2.3.7. Solid-State Detector; 2.3.8. Image Current Detection; References; 3 TANDEM MASS SPECTROMETRY; 3.1. Tandem MS Analyzer Combinations; 3.1.1. Tandem-in-Space; 3.1.2. Tandem-in-Time; 3.1.3. Other Tandem MS Configurations; 3.2. Ion Activation Methods; 3.2.1. In-Source Decay; 3.2.2. Post-Source Decay; 3.2.3. Collision Induced/Activated Dissociation; 3.2.4. Photodissociation

3.2.5. Blackbody Infrared Radiative Dissociation 3.2.6. Electron Capture Dissociation; 3.2.7. Electron Transfer Dissociation; 3.2.8. Surface-Induced Dissociation; References; 4 SEPARATION METHODS; 4.1. Chromatography; 4.1.1. Gas Chromatography; 4.1.2. Liquid Chromatography; 4.1.3. Supercritical Fluid Chromatography; 4.2. Electric-Field Driven Separations; 4.2.1. Ion Mobility; 4.2.2. Electrophoresis; References; PART II INTERPRETATION; 5 INTRODUCTION TO MASS SPECTRA INTERPRETATION: ORGANIC CHEMISTRY; 5.1. Basic Concepts; 5.2. Inlet Systems; 5.2.1. Direct Inlet

5.2.2. Chromatography-Mass Spectrometry 5.3. Physical Bases of Mass Spectrometry; 5.3.1. Electron Ionization; 5.3.2. Basics of Fragmentation Processes in Mass Spectrometry; 5.3.3. Metastable Ions; 5.4. Theoretical Rules and Approaches to Interpret Mass Spectra; 5.4.1. Stability of Charged and Neutral Particles; 5.4.2. The Concept of Charge and Unpaired Electron Localization; 5.4.3. Charge Remote Fragmentation; 5.5. Practical Approaches to Interpret Mass Spectra; 5.5.1. Molecular Ion; 5.5.2. High Resolution Mass Spectrometry

5.5.3. Determination of the Elemental Composition of Ions on the Basis of Isotopic Peaks

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

9786612687563

9781282687561

1282687565

9780470395813

0470395818

9780470395806

047039580X

OCLC:

476225670