Mass spectrometry handbook / edited by Mike S. Lee.

Format:

Book

Contributor:

Lee, Mike S., 1960-

Series:

Wiley series on pharmaceutical science and biotechnology: practices, applications and methods.

Wiley series on pharmaceutical science and biotechnology: practices, applications and methods

Language:

English

Subjects (All):

Mass spectrometry--Handbooks, manuals, etc.

Mass spectrometry.

Spectrum analysis.

Physical Description:

1 online resource (1340 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, NJ : J. Wiley & Sons, c2012.

Language Note:

English

Summary:

Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.

Contents:

Intro

MASS SPECTROMETRY HANDBOOK

CONTENTS

FOREWORD

PREFACE

CONTRIBUTORS

SECTION I: BIOTECHNOLOGY/PROTEINS

1: TARGETED PROTEOMICS USING IMMUNOAFFINITY PURIFICATION

2: MASS SPECTROMETRY-BASED METHODS TO INVESTIGATE POSTTRANSLATIONAL PROTEIN MODIFICATIONS BY LIPID PEROXIDATION PRODUCTS

3: IMAGING MASS SPECTROMETRY (IMS) FOR BIOLOGICAL APPLICATION

4: METHODOLOGIES FOR IDENTIFYING MICROORGANISMS AND VIRUSES BY MASS CATALOGING OF RNAs

SECTION II: PHARMACEUTICAL

5: PRECLINICAL PHARMACOKINETICS: INDUSTRIAL PERSPECTIVE

6: LC-MS IN DRUG METABOLISM AND PHARMACOKINETICS: A PHARMACEUTICAL INDUSTRY PERSPECTIVE

7: QUANTITATIVE MASS SPECTROMETRY IN SUPPORT OF PHARMACOKINETIC STUDIES

8: DETERMINATION OF PHARMACOKINETIC PARAMETERS BY HPLC-MS/MS AND UPLC-MS/MS

9: METHODS FOR SCREENING ENANTIOSELECTIVE INTERACTIONS IN THE SOLUTION PHASE USING ESI-MS

10: HYDROGEN/DEUTERIUM EXCHANGE MASS SPECTROMETRY (HDX MS) IN THE STUDIES OF ARCHITECTURE, DYNAMICS, AND INTERACTIONS OF BIOPHARMACEUTICAL PRODUCTS

11: TOF-SIMS APPLICATIONS TO BIOIMAGING AND BIOMOLECULE EVALUATION METHODS

12: ACCELERATOR MASS SPECTROMETRY IN PHARMACEUTICAL DEVELOPMENT

SECTION III: CLINICAL ANALYSIS

13: MASS SPECTROMETRY IN CLINICAL ANALYSIS: SCREENING FOR INBORN ERRORS IN METABOLISM

14: MASS SPECTROMETRY FOR STEROID ANALYSIS

SECTION IV: FORENSICS

15: FORENSIC APPLICATIONS OF ISOTOPE RATIO MASS SPECTROMETRY

16: ANALYSIS OF TRIACETONE TRIPEROXIDE EXPLOSIVE BY MASS SPECTROMETRY

SECTION V: SPACE EXPLORATION

17: MASS SPECTROMETRY IN SOLAR SYSTEM EXPLORATION

18: APPLICATION OF GC × GC-TOFMS TO THE CHARACTERIZATION OF EXTRATERRESTRIAL ORGANIC MATTER

SECTION VI: HOMELAND SECURITY

19: METHODS OF MASS SPECTROMETRY IN HOMELAND SECURITY APPLICATIONS

20: HOMELAND SECURITY

21: MASS SPECTROMETRY IN HOMELAND SECURITY.

22: MEASUREMENTS OF SURFACE CONTAMINANTS AND SORBED ORGANICS USING AN ION TRAP SECONDARY ION MASS SPECTROMETER

23: DETERMINATION OF ACTINIDES: DETERMINATION OF LOW-CONCENTRATION URINE URANIUM 235/238 ISOTOPE RATIOS

SECTION VII: FOOD ANALYSIS

24: MASS SPECTROMETRY IN AGRICULTURE, FOOD, AND FLAVORS: SELECTED APPLICATIONS

25: TOP-DOWN PROTEOMIC IDENTIFICATION OF PROTEIN BIOMARKERS OF FOOD-BORNE PATHOGENS USING MALDI-TOF-TOF-MS/MS

SECTION VIII: ENVIRONMENTAL

26: DETERMINATION OF DITHIOCARBAMATE FUNGICIDES IN FOOD BY HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY

27: DISINFECTANT AND BY-PRODUCT ANALYSIS IN WATER TREATMENT BY MEMBRANE INTRODUCTION MASS SPECTROMETRY

28: PROTON TRANSFER REACTION MASS SPECTROMETRY (PTR-MS)

29: DETERMINATION OF CHLORINATED COMPOUNDS IN DIALYSIS WATER AND IN BIOLOGICAL FLUIDS/MATRICES

SECTION IX: GEOLOGICAL

30: MASS SPECTROMETRY TECHNIQUES FOR ANALYSIS OF OIL AND GAS TRAPPED IN FLUID INCLUSIONS

31: LA-MC-ICP-MS APPLIED TO U-PB ZIRCON GEOCHRONOLOGY

32: HYDROCARBON PROCESSING

33: HYDROCARBON PROCESSING: MALDI-MS OF POLYDISPERSE HYDROCARBON SAMPLES

34: RENEWABLE ENERGY: MASS SPECTROMETRY IN BIOFUEL RESEARCH

SECTION X: ARCHAEOLOGY

35: MASS SPECTROMETRY IN ARCHAEOLOGY

36: ARCHAEOMETRIC DATA FROM MASS SPECTROMETRIC ANALYSIS OF ORGANIC MATERIALS: PROTEINS, LIPIDS, TERPENOID RESINS, LIGNOCELLULOSIC POLYMERS, AND DYESTUFF

37: LASER ABLATION ICP-MS IN ARCHAEOLOGY

38: SPATIALLY RESOLVED MS IN THE STUDY OF ART AND ARCHAEOLOGICAL OBJECTS

39: LASER ABLATION-INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY FOR THE INVESTIGATION OF ARCHAEOLOGICAL SAMPLES

SECTION XI: SURFACE ANALYSIS

40: MASS SPECTROMETRY IN SEMICONDUCTOR RESEARCH

41: ANALYSIS OF THIN AND THICK FILMS

42: SIMS FOR ORGANIC FILM ANALYSIS.

43: CERAMICS: CONTRIBUTION OF SECONDARY ION MASS SPECTROMETRY (SIMS) TO THE STUDY OF CRYSTAL CHEMISTRY OF MICA MINERALS

SECTION XII: POLYMERS

44: ETV-ICPMS FOR ANALYSIS OF POLYMERS

45: POLYMERS

46: MASS SPECTROSCOPY IN POLYMER RESEARCH

47: LASER MASS SPECTROMETRY APPLIED TO THE ANALYSIS OF POLYMERS

SECTION XIII: ANALYTICAL TECHNIQUES

48: MEASURING THERMODYNAMIC PROPERTIES OF METALS AND ALLOYS

49: HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY-MASS SPECTROMETRY FOR ANALYSIS OF SMALL MOLECULES

50: LASER IONIZATION MASS SPECTROMETRY OF INORGANIC IONS

51: MASS SPECTROMETRY IN THE SSITKA STUDIES

52: PROTON TRANSFER REACTION MASS SPECTROMETRY: APPLICATIONS IN THE LIFE SCIENCES

INDEX.

Notes:

Includes index.

ISBN:

9786613622426

9781280592591

1280592591

9781118180723

1118180720

9781118180730

1118180739

9781118180709

1118180704

OCLC:

787842595