Drug monitoring by HPLC : recent developments / Victoria Samanidou and Eftichia Karageorgou.

Format:

Book

Author/Creator:

Samanidou, Victoria.

Contributor:

Karageorgou, Eftichia.

Series:

Pharmacology-research, safety testing, and regulation series.

Pharmacology : research, safety testing and regulation series

Language:

English

Subjects (All):

High performance liquid chromatography.

Drugs--Analysis.

Drugs.

Physical Description:

1 online resource (viii, 127 pages) : illustrations

Edition:

1st ed.

Place of Publication:

New York : Nova Science Publishers, 2010.

Language Note:

English

Summary:

Recently HPLC-MS/MS has gained increasing popularity in clinical laboratories due to the advantages of the technology over other methods, while the capital cost for instruments has been decreased. HPLC-MS/MS provides high specificity and sensitivity for the simultaneous measurement of several drugs and/or their major metabolites in one single analytical run. In this new book chromatographic methods published in the last decade are reviewed regarding their applicability to drug monitoring. HPLC methods for anti-cancer drugs, bronchodilators, cardiovascular drugs, antipsychotics, antibiotics, antiepileptic drugs, antidepressants, and immunosuppressants have been presented comprehensively regarding sample preparation and chromatographic separation. Supportive information has been included on HPLC analysis and sample preparation.

Contents:

Brief introduction to HPLC

Sample preparation

Anti-cancer drugs

Bronchodilators

Cardiovascular drugs

Antipsychotics

Antibiotics

Antiepileptic drugs

Antidepressants

Immunosuppressants.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-61324-472-X

OCLC:

738478405