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Multiple myeloma : symptoms, diagnosis and treatment / Milen Georgiev and Evgeni Bachev, editors.
- Format:
- Book
- Series:
- Cancer etiology, diagnosis, and treatments.
- Cancer etiology, diagnosis and treatments series
- Language:
- English
- Subjects (All):
- Multiple myeloma.
- Physical Description:
- 1 online resource (283 p.)
- Edition:
- 1st ed.
- Place of Publication:
- New York : Nova Biomedical Books, c2009.
- Language Note:
- English
- Summary:
- Multiple myeloma (also known as myeloma or plasma cell myeloma) is a progressive hematologic disease. It is a cancer of the plasma cell, an important part of the immune system that produces immunoglobulins (antibodies) to help fight infection and disease. Multiple myeloma is characterized by excessive numbers of abnormal plasma cells in the bone marrow and overproduction of intact monoclonal immunoglobulin or Bence-Jones protein. Hypercalcemia, anemia, renal damage, increased susceptibility to bacterial infection, and impaired production of normal immunoglobulin are common clinical manifestations of multiple myeloma. It is often also characterized by diffuse osteoporosis, usually in the pelvis, spine, ribs, and skull. This new book gathers the latest research from around the globe on multiple myeloma research and related topics such as immune defects in multiple myeloma, surgical options in the treatment of spinal myeloma, the role of PBSC in multiple myeloma and allogeneic stem cell transplantation.
- Contents:
- Measurement of proliferative and apoptotic indices in myeloma plasmocytes / J. Minarik and V. Scudla
- Wnt signaling pathways in multiple myeloma / Ya-Wei Qiang and Stuart Rudikoff
- The activation of transcription factor NF-kappaB in multiple myeloma and its role in therapy of this malignancy / Ota Fuchs
- Proteasome inhibition as a therapeutic strategy in patients with multiple myeloma / Ota Fuchs
- Plasma cell dyscrasias / Cherie H. Dunphy
- Bisphosphonates in multiple myeloma patients / Jasmina Redzepovic, Ronald Gust and Heinz Pertz
- Immune defects in multiple myeloma / Krzysztof Giannopoulos, Iwona Hus and Anna Dmoszynska
- Surgical options in the treatment of spinal myeloma / M. Repko ... [et al.]
- The role of PBSC in multiple myeloma : from biology to treatment / Alessandro Corso, Patrizia Zappasodi and Marzia Varettoni
- Autologous and allogeneic stem cell transplantation for multiple myeloma / Evangelos Terpos and John Meletis.
- Notes:
- Description based upon print version of record.
- Includes bibliographical references and index.
- ISBN:
- 1-61728-542-0
- OCLC:
- 923664518
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