Biomaterials developments and applications / Henri Bourg and Amaury Lisle, editors.

Format:

Book

Contributor:

Bourg, Henri.

Lisle, Amaury.

Series:

Advances in biology and medicine series.

Advances in biology and medicine series

Language:

English

Subjects (All):

Biomedical materials.

Biomedical engineering.

Physical Description:

1 online resource (513 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Science Publishers, c2010.

Language Note:

English

Summary:

Despite the huge impact that biomaterials have had on patients' quality of life, improvements in device performance and the development of alternatives to augment available therapies are continuously being sought. This book explores the development and application of biomaterials over the past 25 years, examining the current clinical demand, the scientific rationale, and the technical challenges to be overcome. Furthermore, this book introduces the blood components involved in hemostasis and thrombosis, followed by the common biomaterials applied in blood-contacting devices. The complications induced by the interactions between blood and biomaterials is also briefly addressed, as well as the commonly used techniques for improving biomaterials' hemocompatibility. In addition, the authors give some valuable insight into calcium orthophosphate cements and concretes, as excellent biomaterials suitable for both dental and bone grafting application. Despite the growth of potential hydrogel based therapies, the route to market for new products is constrained by the need to develop an appropriate regulatory and metrological framework under which they will be assessed. This book outlines the role that metrology has to play in the regulation of emerging hydrogel-based therapies and detail possible strategies for assessing their safety and effectiveness. Other chapters examine the surface of CoCrMo alloy prior and after exposure into different solutions simulating oral conditions, recent research on delivery of gold nanoparticles inside the cells and their potential applications in nanomedicine, and the widely used biomedical applications for hydrogels.

Contents:

""BIOMATERIALS DEVELOPMENTSAND APPLICATIONS""; ""CONTENTS""; ""PREFACE""; ""CALCIUM ORTHOPHOSPHATE-BASEDBIOCOMPOSITES AND HYBRID BIOMATERIALS""; ""ABSTRACT""; ""INTRODUCTION""; ""GENERAL INFORMATION ONCOMPOSITES AND BIOCOMPOSITES""; ""THE MAJOR CONSTITUENTMATERIALS OF BIOCOMPOSITES FORBIOMEDICAL APPLICATIONS""; ""3.1. Calcium Orthophosphates""; ""3.2. Polymers""; ""3.3. Inorganic Materials and Compounds (Metals, Ceramics, Glass, Oxides,Carbon, Etc.)""; ""CALCIUM ORTHOPHOSPHATE-BASEDBIOCOMPOSITES AND HYBRID BIOMATERIALS""; ""4.1. Biocomposites with Polymers""; ""Apatite-Based Biocomposites""

""TCP-Based Biocomposites""""Other Calcium Orthophosphate-Based Biocomposites""; ""4.2. Calcium Orthophosphate Cement-Based Biocomposites and Concretes""; ""4.3. Nano-Calcium Orthophosphate-Based Biocomposites and Nano-Biocomposites""; ""4.4. Biocomposites with Collagen""; ""4.5. Biocomposites with Other BioorganicCompounds and Biological Macromolecules""; ""4.6. Injectable Bone Substitutes (IBS)""; ""4.7. Biocomposites with Glasses, Inorganic Materials and Metals""; ""4.8. Functionally Graded Biocomposites""; ""4.9. Biosensors""

""INTERACTION BETWEEN THE PHASES IN CALCIUMORTHOPHOSPHATE-BASED BIOCOMPOSITES""""BIOACTIVITY AND BIODEGRADATION OF CALCIUMORTHOPHOSPHATE-BASED BIOCOMPOSITES""; ""SOME CHALLENGES AND CRITICAL ISSUES""; ""CONCLUSIONS""; ""REFERENCES""; ""NOMENCLATURE""; ""CALCIUM ORTHOPHOSPHATE CEMENTSAND CONCRETES""; ""ABSTRACT""; ""1. INTRODUCTION""; ""2. CALCIUM ORTHOPHOSPHATE CEMENTS""; ""3. TWO MAJOR TYPES OF CALCIUM ORTHOPHOSPHATE CEMENTS""; ""3.1. Apatite Cements""; ""3.2. Brushite Cements""; ""4. VARIOUS PROPERTIES OF CALCIUM ORTHOPHOSPHATE CEMENTS""

""5. BIORESORPTION AND REPLACEMENT OF THE CEMENTS BY BONES""""6. THE MECHANICAL PROPERTIES""; ""7. REINFORCED CALCIUM ORTHOPHOSPHATE CEMENT COMPOSITESAND CONCRETES""; ""8. CLINICAL AND MEDICAL APPLICATIONS""; ""8.1. Dental Applications""; ""8.2. Craniofacial and Maxillofacial Applications""; ""8.3. Orthopedic Applications""; ""8.4. Vertebroplasty and Kyphoplasty Applications""; ""8.5. Drug Delivery Applications""; ""8.6. Brief Conclusions on the Medical Applications""; ""9. FUTURE DEVELOPMENTS""; ""10. CONCLUSIONS""; ""REFERENCES""; ""HYDROGELS IN BIOLOGY AND MEDICINE""; ""ABSTRACT""

""1. INTRODUCTION""""2. STRUCTURE OF HYDROGELS IN RELATION TO THE FORMATIONCONDITIONS""; ""2.1. General Features of Network Build-Up""; ""2.2. Physical Polymer Hydrogels""; ""2.3. Inter- and Intramolecular Crosslinking""; ""2.4. Ways of Formation of Polymer Hydrogels""; ""2.5. Special Features of Polymerization in Presence of Diluents. PhaseSeparation - Macrosyneresis vs. Microsyneresis""; ""3. SWELLING AND MECHANICAL PROPERTIES OF HYDROGELS""; ""3.1. Swelling Properties of Hydrogels""; ""3.1.1. Equilibrium swelling""; ""Role of the interaction parameter Ï?""

""Effect of degree of crosslinking""

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-61209-862-2

OCLC:

923654672