Drug metabolism prediction / edited by Johannes Kirchmair.

Format:

Book

Contributor:

Kirchmair, Johannes, editor.

Series:

Methods and principles in medicinal chemistry.

Methods and Principles in Medicinal Chemistry

Language:

English

Subjects (All):

Drugs--Metabolism.

Drugs.

Enzymes--Effect of drugs on.

Enzymes.

Physical Description:

1 online resource (538 p.)

Edition:

1st ed.

Place of Publication:

Weinheim, Germany : Wiley-VCH, 2014.

Language Note:

English

Summary:

The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists.The authors provide more than a systematic overview of computational tools and knowledge bases for drug metabolism research and their underlying principles. They aim to convey their expert knowledge distilled from many years of experience in the field. In addition to the fundamentals, computational approaches and their applications, this volume provides expert accounts of the latest experimental methods for investigating drug metabolism in four dedicated chapters. The authors

Contents:

Part 1. Introduction

Part 2. Software, web servers and data resources to study metabolism

Part 3. Computational approaches to study cytochrome P450 enzymes

Part 4. Computational approaches to study sites and products of metabolism

Part 5. Computational approaches to study enzymes inhibition and induction

Part 6. Experimental approaches to study metabolism.

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on online resource; title from PDF title page (ebrary, viewed July 8, 2014).

ISBN:

9783527673018

3527673016

9783527673261

3527673261

9783527672998

3527672990

OCLC:

882609174