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Bioisosteres in medicinal chemistry / edited by Nathan Brown.
- Format:
- Book
- Series:
- Methods and principles in medicinal chemistry ; v. 54.
- Methods and principles in medicinal chemistry ; v. 54
- Language:
- English
- Subjects (All):
- Pharmaceutical chemistry.
- Physical Description:
- 1 online resource (258 p.)
- Edition:
- 1st ed.
- Place of Publication:
- Weinheim, Germany : Wiley-VCH, 2012.
- Language Note:
- English
- Summary:
- Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism.As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development.The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered,while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third partcovers the four
- Contents:
- pt. 1. Principles
- pt. 2. Data
- pt. 3. Methods
- pt. 4. Applications.
- Notes:
- Description based upon print version of record.
- Includes bibliographical references and index.
- ISBN:
- 9786613688927
- 9783527654321
- 3527654321
- 9781280778537
- 1280778539
- 9783527654307
- 3527654305
- 9783527654338
- 352765433X
- OCLC:
- 809920141
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