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Development of new MDR-tuberculosis drugs / Jarmila Vinšová and Martin Krátký.
- Format:
- Book
- Author/Creator:
- Vinšová, Jarmila.
- Series:
- Pharmacology-research, safety testing, and regulation series.
- Pharmacology-research, safety testing and regulation
- Language:
- English
- Subjects (All):
- Antitubercular agents.
- Multidrug-resistant tuberculosis--Chemotherapy.
- Multidrug-resistant tuberculosis.
- Physical Description:
- 1 online resource (112 p.)
- Edition:
- 1st ed.
- Place of Publication:
- New York : Nova Science Publishers/Nova Biomedical, c2010.
- Language Note:
- English
- Summary:
- The emergence of resistance to anti-tuberculosis drugs, particularly of MDR-TB and newly XDR-TB, has become a major public health problem. The current treatment regiment has several disadvantages, i.e. long treatment period (DOTS takes minimum 6 months) during which tubercle bacilli mutant become resistant to one or more drugs; side effects of the used drugs; co-infection of HIV/AIDS. The emergence of MDR-TB has made many currently available anti-TB drugs ineffective. Sleeping latent forms of mutant bacilli resistant against common anti-TB drugs pose the risk of epidemic for the new generation. This book outlines the recent advances in the development of new multi-drug-resistant tuberculosis (MDR-TB) drugs.
- Contents:
- Resistance to commonly used drugs, mechanism of the action
- Research of novel MDR potential drugs.
- Notes:
- Description based upon print version of record.
- Includes bibliographical references and index.
- Description based on print version record and CIP data provided by publisher.
- ISBN:
- 1-61668-478-X
- OCLC:
- 923662021
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