Antimicrobial peptides : discovery, design, and novel therapeutic strategies / edited by Guangshun Wang.

Format:

Book

Contributor:

Wang, Guangshun.

Series:

Advances in molecular and cellular microbiology ; 18.

Advances in molecular and cellular microbiology ; 18

Language:

English

Subjects (All):

Peptide antibiotics.

Pharmaceutical chemistry.

Physical Description:

1 online resource (xvii, 230 pages) : illustrations

Edition:

18th ed.

Place of Publication:

Wallingford, Oxfordshire, UK : CABI, c2010.

Language Note:

English

Summary:

Antimicrobial Peptides (AMPs) are an organism's built-in defence molecules that have attracted extensive research attention worldwide. Harnessing and creating them synthetically has the potential to help overcome increasing antibiotic resistance in many pathogens. In addition to covering the current advances in AMP research, this volume examines new technologies such as bioinformatics, combinatorial libraries, high-throughput screening, peptidomimetics, biophysics, and structural biology. This volume also describes new methods and strategies for AMP prediction, design, and applications that ov

Contents:

Contents; Contributors; Preface; Introduction; PART I: NATURAL ANTIMICROBIAL PEPTIDES: NOMENCLATURE, CLASSIFICATION AND INTERESTING TEMPLATES FOR PEPTIDE ENGINEERING; PART II: EXPANDING THE PEPTIDE SPACE: PREDICTION METHODS, DESIGN STRATEGIES AND PEPTIDOMIMETICS; PART III: BIOPHYSICS, STRUCTURAL BIOLOGY AND MECHANISM OF ACTION OF ANTIMICROBIAL PEPTIDES; PART IV: NOVEL THERAPEUTIC STRATEGIES TO BOLSTER HOST DEFENCE; Index

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-282-89349-1

9786612893490

1-84593-694-9

OCLC:

688480203