Ventricular fibrillation and acute coronary syndrome / editor, Joyce E. Mandell.

Format:

Book

Contributor:

Mandell, Joyce E.

Series:

Cardiology research and clinical developments.

Cardiology research and clinical developments

Language:

English

Subjects (All):

Coronary heart disease.

Ventricular fibrillation.

Physical Description:

1 online resource (248 p.)

Edition:

1st ed.

Place of Publication:

Hauppauge, NY : Nova Science, 2011.

Language Note:

English

Summary:

Ventricular fibrillation is a cause of cardiac arrest and sudden cardiac death. The ventricular muscle twitches randomly, rather than contracting in a co-ordinated fashion (from the apex of the heart to the outflow of the ventricles), and so the ventricles fail to pump blood into the arteries and into systemic circulation. Ventricular fibrillation is a sudden lethal arrhythmia responsible for many deaths mostly brought on by ischaemic heart disease. Acute coronary syndrome (ACS) is a set of signs and symptoms related to the heart. ACS is compatible with a diagnosis of acute myocardial ischemia. This book presents current research from across the globe in the study of ventricular fibrillation and acute coronary syndrome, including clopidogrel response in acute coronary syndrome; primary ventricular fibrillation in "tako-tsubo" syndrome; and ECG predictors of fibrillatory events.

Contents:

""VENTRICULAR FIBRILLATION AND ACUTE CORONARY SYNDROME""; ""VENTRICULAR FIBRILLATION AND ACUTE CORONARY SYNDROME""; ""CONTENTS ""; ""PREFACE""; ""CLOPIDOGREL RESPONSE IN ACUTE CORONARY SYNDROME: CLINICAL IMPLICATIONS AND EMERGING THERAPIES ""; ""ABSTRACT ""; ""ABBREVIATIONS LIST ""; ""INTRODUCTION ""; ""RESISTANCE/VARIABLE RESPONSE TO CLOPIDOGREL. DOES IT EXIST? ""; ""MECHANISMS OF VARIABLE RESPONSE TO CLOPIDOGREL ""; ""Genetic Polymorphism ""; ""Drug-Drug Interactions ""; ""Statins ""; ""Proton Pump Inhibitors ""; ""Calcium-Channel Blockers ""

""IS IT POSSIBLE TO ACCURATELY ASSESS THE INHIBITORY EFFECT OF ANTIPLATELT DRUGS? """"CLINICAL IMPLICATIONS OF VARIABLE RESPONSE TO CLOPIDOGREL ""; ""Drug Eluting Stent""; ""WHAT TO DO WITH PATIENTS WITH REDUCED RESPONSE TO CLOPIDOGREL THERAPY? ""; ""Optimise Clopidogrel Response According to Platelet Function Tests ""; ""EMERGING THERAPIES ""; ""Prasugrel ""; ""Ticagrelor ""; ""Cangrelor ""; ""REFERENCES ""; ""PROTEOMICS OF ACUTE CORONARY SYNDROME ""; ""1. INTRODUCTION ""; ""2. PLASMA ""; ""3. BLOOD CELLS IN ACUTE CORONARY SYNDROME ""; ""3.1. Circulating Monocytes ""; ""3.2 Platelets ""

""3.3. Proteomics on Vascular Progenitors """"Endothelial Progenitor Cells (EPC) ""; ""4. TISSUE PROTEOMICS ""; ""Secretome ""; ""5. METABOLOMICS""; ""ABBREVIATIONS""; ""PROTEINS ABBREVIATIONS ""; ""REFERENCES ""; ""MAJOR BLEEDING IN ACUTE CORONARY SYNDROME: DEFINITIONS, MAGNITUDE OF THE PROBLEM, PREDICTORS, OUTCOMES, MANAGEMENT, AND PREVENTION ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""DEFINITIONS OF MAJOR BLEEDING IN ACS ""; ""MAGNITUDE OF THE PROBLEM ""; ""PREDICTORS OF MAJOR BLEEDING ""; ""Age ""; ""Gender ""; ""History of Bleeding ""; ""Renal Impairment ""; ""Type of ACS ""

""Killip Class """"Diabetes Mellitus ""; ""Choice of Antiplatelet, Antithrombotic, and Fibrinolytic Agents""; ""Invasive Procedures ""; ""Blood Transfusion ""; ""Anemia ""; ""HOSPITAL OUTCOMES AND MAJOR BLEEDING ""; ""Mechanisms by Which Major Bleeding Affects Outcomes ""; ""Prevention and Management ""; ""CONCLUSION ""; ""REFERENCES""; ""NOVEL ANTIPLATELETS IN ACUTE CORONARY SYNDROMES ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""ASPIRIN (ACETYLSALICYLIC ACID, ASA) ""; ""THIENOPYRIDINES ""; ""Ticlopidine ""; ""Clopidogrel ""; ""Prasugrel ""; ""Cangrelor (ARC-69931MX) ""; ""Ticagrelor (AZD6140) ""

""Elinogrel """"Bx667 ""; ""THROMBOXANE RECEPTOR ANTAGONISTS ""; ""Terutroban (S18886) ""; ""von Willebrand Factor Inhibitors ""; ""Ajw200 ""; ""Arc1779 ""; ""Alx-0081 ""; ""DIRECT THROMBIN INHIBITORS (PAR-1 INHIBITORS) ""; ""Sch 530348 ""; ""E5555 ""; ""CONCLUSION ""; ""REFERENCES ""; ""UNCONTROLLED IMMUNE RESPONSE IN ACUTE MYOCARDIAL INFARCTION ""; ""ABSTRACT""; ""INTRODUCTION ""; ""LEUKOCYTES ""; ""NEUTROPHILS ""; ""MONOCYTES ""; ""LYMPHOCYTES ""; ""Rationale and Clinical Evidence ""; ""Effector T-Cells ""; ""Regulatory T-Cells ""; ""The Inverted Pyramid Model ""

""THERAPEUTIC OPPORTUNITIES ""

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-61761-167-0

OCLC:

775352327