Acquired brain injury in the fetus and newborn / Michael Shevell, Steven Miller.

Format:

Book

Author/Creator:

Shevell, Michael.

Contributor:

Miller, Steven P. (Pediatrician)

Series:

1st

Language:

English

Subjects (All):

Fetal brain--Diseases.

Fetal brain.

Newborn infants--Wounds and injuries.

Newborn infants.

Physical Description:

1 online resource (340 p.)

Edition:

1st ed.

Place of Publication:

Cambridge : Mac Keith Press : [distributor] John Wiley and Sons Ltd : [distributor] John Wiley & Sons Australia Ltd : [distributor] John Wiley & Sons Australia Ltd : [distributor] John Wiley & Sons, 2012.

Language Note:

English

Summary:

Expert synthesis of acquired brain injuries from the fetus to the term newborn to improve diagnosis and care is presented in this authoritative book, including recent significant advances. This book focuses on specific populations encountered regularly by clinicians, practicing neurologists, neonatologists and paediatricians.

Contents:

Contents; Authors' Appointments; Foreword; Preface; Acknowledgments; 1 Brain Injury in the Fetus; Introduction; Overview of normal fetal brain development; Normal function of the maternal placenta-fetal interface; Mechanisms of fetal brain injury; Fetal errors of metabolism; Conclusions; 2 Imaging the Fetal Brain; Introduction; Imaging the fetal brain: ultrasound versus magnetic resonance imaging; Imaging the fetal brain: the role of conventional magnetic resonance imaging; Normal fetal brain development on conventional magnetic resonance imaging

Fetal brain injury in the fetus on conventional magnetic resonance imaging Advanced magnetic resonance imaging techniques in the ex utero infant; Acquired fetal brain injury and advanced in vivo fetal magnetic resonance imaging techniques; Summary; 3 Mechanisms of Acute and Chronic Brain Injury in the Preterm Infant ; Magnitude of the problem and spectrum of brain injury in preterm survivors; Patholologic features of brain injury in preterm infants; Pathophysiology of cerebral white matter injury; Cellular-molecular mechanisms of acute whitematter injury

Cellular mechanisms of chronic white matter injury: myelination failure and the susceptibility of oligodendrocytes and axons Is acquired chronic brain injury in preterm infants necessarily static and irreparable?; Clinical implications of potentially arrested white matter development; 4 Clinical assessment of the Preterm Infant including Near-infrared spectroscopy, amplitude-integrated Electroencephalography, and Electroencephalography; Near-infrared spectroscopy-monitored regional cerebral oxygen saturation; Electroencephalography and amplitude-integratedEEG; Conclusion

5 Imaging the Brain of the Preterm Infant Introduction; Magnetic resonance imaging of the brain in the normal preterm infant; Magnetic resonance imaging of brain injury in the preterm infant; Quantitative magnetic resonance studies of the developing brain in the preterm infant and association with neurodevelopmental outcome; 6 Protecting the Brain of the Preterm Infant; Introduction; Intraventricular hemorrhage; Posthemorrhagic ventricular dilation; White matter injury; Cerebellar injury; Antenatal neuroprotective agents; Developmental care and nutrition

Emerging candidates for future neuroprotective investigations Conclusions; 7 Seizures in the Preterm Infant; Introduction; Epidemiology; Clinical features; Differential diagnosis; Investigations including imaging; Treatment and management; Short- and long-term outcomes; Implications for future research; 8 Outcomes After Brain Injury in the Preterm Infant; Motor impairment; Cognitive impairment; Behavioral and psychiatric disorders; Conclusion; 9 Mechanisms of Brain Neurodegeneration in the Term Infant; Introduction; Types of cell death

Molecular and cellular mechanisms of cell death in the immature brain

Notes:

Description based upon print version of record.

Description based on publisher supplied metadata and other sources.

ISBN:

9781907655364

1907655360

OCLC:

929120224