Protein degradation in health and disease.

Format:

Book

Conference/Event

Conference Name:

Symposium on Protein Degradation in Health and Disease (1979 : Ciba Foundation)

Series:

Ciba Foundation symposium ; new ser. 75.

Ciba Foundation symposium ; 75 (new ser.)

Language:

English

Subjects (All):

Proteins--Metabolism--Congresses.

Proteins.

Proteolytic enzymes--Congresses.

Proteolytic enzymes.

Physiology, Pathological--Congresses.

Physiology, Pathological.

Physical Description:

1 online resource (430 pages) : illustrations

Edition:

1st ed.

Place of Publication:

Amsterdam ; New York : Excerpta Medica, 1980.

Language Note:

English

Summary:

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Contents:

Protein Degradation in Health and Disease; Contents; Discussion; Introduction: the classification of proteinases; Discussion; Lysosomal cysteine proteinases; Discussion; Cathepsin D: the lysosomal aspartic proteinase; Discussion; Human leucocyte elastase and cathepsin G: structural and functional characteristics; Discussion; Human collagenases: comparative and immunolocalization studies; Discussion; Proteinases in connective tissue breakdown; Discussion; Cellular mechanisms of proteinase release from inflammatory cells and the degradation of extracellular proteins; Discussion

Inactivation of cytosol enzymes by a liver membrane protein; Discussion; Lysosomes and protein degradation; Discussion; Insights into mechanisms of intracellular protein turnover from studies on pinocytosis; Discussion; Turnover and degradation of mitochondria and their proteins; Discussion; Protein degradation in cells in culture; Discussion; Regulation of protein breakdown in hepatocyte monolayers; Discussion; A possible role for neutral proteolysis in the degradation of intracellular proteins; Discussion; Studies of the ATP dependence of protein degradation in cells and cell extracts

Discussion; Coordination of protein synthesis and degradation; Discussion; General discussion Sites of protein degradation; Application of liver perfusion as an in vitro model in studies of intracellular protein degradation; Protein degradation and the regulation of protein balance in muscle; Discussion; Protein degradation in metabolic and nutritional disorders; Discussion; Proteinase inhibitors in severe inflammatory processes (septic shock and experimental endotoxaemia): biochemical, pathophysiological and therapeutic aspects; Discussion; Neutral proteinases of leucocytes and the inflammatory process; Discussion; Final general discussion; Concluding remarks; Index of contributors; Subject index

Notes:

Description based upon print version of record.

Includes bibliographical references and indexes.

ISBN:

9786613694324

9781280783937

1280783931

9780470720585

0470720581

9780470718261

0470718269

OCLC:

797918458