Estrogens : biochemistry, therapeutic uses and physiological effects / Vito J. Thompson and Adrion E. Watson, editors.

Format:

Book

Contributor:

Thompson, Vito J.

Watson, Adrion E.

Series:

Endocrinology research and clinical developments.

Endocrinology research and clinical developments

Language:

English

Subjects (All):

Estrogen.

Estrogen--Physiological effect.

Estrogen--Therapeutic use.

Physical Description:

1 online resource (165 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Biomedical, Nova Science Publishers, Inc., 2012.

Language Note:

English

Summary:

Estrogens are a family of hormones that potently regulate reproductive, cardiovascular, bone, brain, and other physiology by altering gene expression. In this book, the authors present topical research in the study of the biochemistry, therapeutic uses and physiological effects of hormones. Topics include the physiological effects of estrogen in fish and its application; estrogens in osteoarthritis and inflammation; estrogens as mediators of obesity-induced inflammation; the transcriptional effect of estrogens on gene expression; and the role of estrogens in regulating the gender disparity of hepatocellular carcinoma.

Contents:

Intro

ESTROGENS: BIOCHEMISTRY, THERAPEUTIC USES AND PHYSIOLOGICAL EFFECTS

Library of Congress Cataloging-in-Publication Data

CONTENTS

PREFACE

Chapter 1: ESTROGENS AS MEDIATORS OF OBESITY-INDUCED INFLAMMATION

ABSTRACT

ABBREVIATIONS

ADIPOSE TISSUE-RELATED INFLAMMATION

ESTROGEN SIGNALING

ESTROGEN TURNOVER IN THE ADIPOSE TISSUE

MODELS OF ESTROGEN INSUFFICIENCY

ESTROGENS AND ADIPOSE TISSUE MASS, DISTRIBUTION AND CELLULARITY

ESTROGENS AND AT INFLAMMATION

XENOESTROGENS AND OBESITY-ASSOCIATED COMPLICATIONS

CONCLUSION

ACKNOWLEDGMENTS

REFERENCES

Chapter 2: EFFECTS OF ESTROGEN USE, FOLLICLE-STIMULATING HORMONE AND LUTEINIZING HORMONE ON COGNITIVE TESTS DEMANDING ATTENTION IN POSTMENOPAUSAL WOMEN

INTRODUCTION

METHOD

Sustained Attention

Attention Span

Word Repetition Span

RESULTS

AUTHOR CONTRIBUTIONS

Chapter 3: THE ROLE OF ESTROGENS IN OSTEOARTHRITIS AND INFLAMMATION

ESTROGEN RECEPTORS STRUCTURE AND CHARACTERISTICS

ESTROGEN ON INFLAMMATION

ESTROGEN AND AUTOIMMUNE DISEASES: RHEUMATOID ARTHRITIS AND SYSTEMIC LUPUS ERYTHEMATOSUS

ESTROGEN AND OSTEOARTHRITIS

COMPETING INTERESTS

Chapter 4: ESTROGEN IN REGULATING THE GENDER DISPARITY OF HEPATOCELLULAR CARCINOMA

HCC OCCURS PREFERENTIALLY IN MALES,WITH THE SEX DIFFERENCE STARTING FROM CHRONIC HEPATITIS

THE INVOLVEMENT OF ANDROGEN AXIS IN PROMOTING MALE HCC

THE INVOLVEMENT OF ESTROGEN AXIS IN PROTECTING FEMALE HCC: EPIDEMIOLOGICAL EVIDENCE AND ANIMAL STUDIES

WILD TYPE AND VARIANT ESTROGEN RECEPTORSIN NORMAL AND HCC LIVER TISSUES

MOLECULAR MECHANISMS FOR THE PROTECTIVE ROLE OF ESTROGEN AXIS IN FEMALE HCC.

THE MECHANISMS OF ESTROGEN AXIS IN PREVENTING HEPATIC FIBROSIS AND STEATOSIS

THE REGULATORY MECHANISMS FOR THE DOWN-REGULATION OF ERa IN FEMALE HCC

THE INTERACTION BETWEEN THE HEPATITISVIRUS B AND ESTROGEN PATHWAY

Chapter 5: POST-TRANSCRIPTIONAL EFFECTS OF ESTROGENS ON GENE EXPRESSION: MESSENGER RNA STABILITYAND TRANSLATION REGULATEDBY MICRORNAS AND OTHER FACTORS

ESTROGENS STABILIZE AND DESTABILIZESPECIFIC MRNAS

ESTROGENS AFFECT MRNA TRANSLATION

ESTROGEN ACTIONS AND MICRORNAS

MicroRNAs - Biogenesis and Regulation of Gene Expression

Estrogens Regulate Expression of MicroRNA Genes in Responsive Tissues during Normal Physiology and Disease

MicroRNAs Regulate ER Gene Expression and Estrogen Actions

FUTURE THERAPEUTIC APPROACHES TO REGULATINGPOST-TRANSCRIPTIONAL ESTROGEN ACTIONS

INDEX.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-62081-749-7

OCLC:

846966045