Motor neuron diseases : causes, classification and treatments / Bradley J. Turner and Julie D. Atkin, editors.

Format:

Book

Contributor:

Turner, Bradley James.

Atkin, Julie.

Series:

Neurology--laboratory and clinical research development series.

Neurology--laboratory and clinical research developments

Language:

English

Subjects (All):

Amyotrophic lateral sclerosis.

Motor neurons--Diseases.

Motor neurons.

Physical Description:

1 online resource (248 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Science Publishers, c2012.

Language Note:

English

Summary:

Motor neuron disease (MND), also commonly known as amyotrophic lateral sclerosis (ALS), is a chronic neurodegenerative disorder of the motor system in adults, characterized by the loss of motor neurons in the cortex, brain stem and spinal cord. This book presents current research from across the globe in the study of the causes, classification and treatments of MND, including membrane trafficking defects as determinants of motor neuron susceptibility and degeneration in ALS; motorneuron specific calcium dysregulation and perturbed cellular calcium homeostasis in ALS; stem cells and their application in ALS treatment; excitotoxicity and selective motor neuron degeneration and therapeutic invervention and assistive technology treatments. (Imprint: Nova Biomedical)

Contents:

Motor neuron disease : causes, classification and treatments / Louisa Ng, Fary Khan

Membrane trafficking defects as determinants of motor neuron susceptibility and degeneration in ALS / Bradley J. Turner, Julie D. Atkin

Motoneuron specific calcium dysregulation and perturbed cellular calcium homestasis in amyotrophic lateral sclerosis : recent advances gained from genetically modified animals and cell culture models / Manoj Kumar Jaiswal

Treatment of ALS utilizing a stem cell strategy / Xiufang Guo, James J. Hickman

Tdp-43-immunoreactive pathology in frontotemporal lobar degeneration with TDP proteinopathy (FTLD-TDP) with and without associated motor neuron disease (MND) / R.A. Armstrong

Excitotoxicity and selective motor neuron degeneration / K.A. Staats, L. Van Den Bosch

Stem cell application in amyotrophic lateral sclerosis : growth factor delivery and cell therapy / Ksenija Bernau, Michael G. Meyer, Masatoshi Suzuki

Therapeutic intervention in spinal and bulbar muscular atrophy (SBMA) / Haruhiko Banno ... [et al.]

Expert commentary : motor neuron disease : assistive technology / Louisa Ng, Fary Khan

Comparative study on application of invasive ventilation and non-invasive ventilation to ALS patients in Europe, the USA, and Japan / Rika Yamauchi, Jun Kawamata, Shun Shimohama

Motor speech disorder in patients with motor neuron disease / Hideto Saigusa

Non-viral gene delivery of the GDNF, either alone or fused to the C-fragment of tetanus toxin protein, prolongs survival in a mouse ALS model / Rosario Osta

Motor neuron disease / Kazumi Murai

Motor neuron disease / Anil Kumar

Bulbospinal muscular atrophy (BSMA) Kennedy's disease / J. Finsterer.

Notes:

"Nova biomedical."

Includes bibliographical references and index.

ISBN:

1-61470-141-5

OCLC:

849929063