Coagulation : kinetics, structure formation and disorders / Anett M. Taloyan and David S. Bankiewicz, editors.

Format:

Book

Contributor:

Taloyan, Anett M.

Bankiewicz, David S.

Series:

Recent advances in hematology research series.

Recent advances in hematology research

Language:

English

Subjects (All):

Blood--Coagulation.

Blood.

Blood coagulation disorders.

Physical Description:

1 online resource (221 p.)

Edition:

1st ed.

Place of Publication:

Hauppauge, N.Y. : Nova Science Publishers, c2012.

Language Note:

English

Summary:

This book presents topical research in the study of the kinetics, structure formation and disorders related to coagulation. Topics discussed include Brownian coagulation and diffusion-limited reactions; deregulation of coagulation during sepsis-induced disseminated intravascular coagulation; substrate induced coagulation (SIC) in aqueous and non-aqueous media for the preparation of advanced battery materials and neonatal coagulation problems. (Imprint: Nova)

Contents:

Intro

COAGULATION

CONTENTS

PREFACE

A NEW APPROACH TO THE THEORY OF BROWNIAN COAGULATION AND DIFFUSION-LIMITED REACTIONS

Abstract

1. Part 1. Brownian Coagulation Theory

1.1. Introduction

1.2. Diffusion Relaxation in Ensemble of Brownian Particles

1.3. Coagulation Rate Equation

1.3.1. Applicability of the Diffusion Approach to Particles Coagulation

1.3.2. Diffusion Mixing Condition

1.4. Kinetic Regime: High Collision Frequency (0 c)

1.5. Kinetic Regime: Low Collision Frequency (0 c)

1.5.1. Continuum Mode (Ra )

1.5.2. Free Molecular Mode (Ra )

1.5.3. Transition Mode (Ra )

1.5.4. Interpolation Formulas

1.5.5. Applicability Range of the Kinetic Approach

1.6. Next Approximation of the Random Walk Theory

1.6.1. Brownian Particles Coagulation

1.6.2. Heavy Vapor Molecules Condensation

1.7. Discussion

CONCLUSION

2. Part 2. Diffusion-Limited Reaction Rate Theory

2.1. Introduction

2.2. Rate Equations

2.2.1. Applicability of the Diffusion Approach to Particles Collisions

2.2.2. Diffusion Mixing Condition

2.2.3. Applicability of the Reaction Rate Equation

2.3. Reaction Rate in 3-D Case

2.3.1. Continuum Mode (BAABBArrRaa,, )

2.3.2. Free Molecular Mode (BAABaaR, )

2.4. Reaction Rate in 2-D Case

2.5. Reaction Rate on 3-D Discrete Lattice

2.6. Reaction Rate on 2-D Discrete Lattice

APPENDIX

ACKNOWLEDGMENTS

REFERENCES

DEREGULATION OF COAGULATION DURING SEPSIS-INDUCED DISSEMINATED INTRAVASCULAR COAGULATION

INTRODUCTION

1. Physiological Coagulation and Fibrinolysis

2. Overview of Sepsis

3. Overview of Disseminated Intravvascular Coagulation

4. Deregulation of Coagulation by Bacteria

5. Deregulation of Fibrinolysis by Bacteria

6. Coagulation Factor and Inhibitor Therapies.

CONCLUSION

Authors' CONTRIBUTIONS

ACKNOWLEDGEMENTS

COAGULATION: KINETIC, STRUCTURE, FORMATION AND DISORDERS

1. Introduction

2. Kinetics of Coagulation Systems and Clot Formation

2.1. Primary Hemostasis

2.2. Coagulation Is Constituted by Interacting Elements

2.3. The Extrinsic Route of Coagulation

2.4. The Intrinsic Route of Coagulation

2.5. The Cellular Model of Coagulation

2.6. Activation of the Coagulation System

3. Kinetics

3.1. Coagulation and Inflammatory Components

3.2. Coagulation and Interaction with Endothelial Cells and Leukocytes

3.3. Cross-Talk between Clotting and Complement System (C)

4. Disorders

4.1. Thrombophilia

4.1.1. Acquired Factors Associated to Thrombosis

4.1.1.1. Procoagulant States and Their Association with Humoral Immunity

4.1.1.2. Concepts of Antibodies in Thrombophilia

4.2. Genetic Factors Associated to Thrombophilia

4.2.1. Deficiency of Antithrombin III

4.2.2. Deficiency of Protein C

4.2.3. Deficiency of Protein S

4.2.4. Mutation of Factor V

4.2.5. Mutation G20210A of Prothrombin

FLOC CHARACTERISTICS AND THE INFLUENCING FACTORS

ABSTRACT

1. INTRODUCTION

2. MATERIALS AND METHODS

2.1. Coagulant Preparation and Characteristics

2.2. Water Samples

2.3. Jar Tests and Floc On-Line Monitor

3. CHARACTERIZATION OF FLOCS FORMED BY DIFFERENT AL-BASED COAGULANTS

3.1. Floc Formation, Breakage and Re-Growth

3.2. Effect of Shear Rate on Floc Size

3.3. Floc Fractal Structure Analysis

4. EFFECT OF PH ON FLOC PROPERTIES

4.1. Effect of PH on Coagulation Efficiency

4.2. Effect of PH on Floc Formation, Breakage and Re-Growth

4.3. Effect of PH on Floc Fractal Structures

REFERENCES.

SUBSTRATE INDUCED COAGULATION (SIC) IN AQUEOUS AND NON-AQUEOUS MEDIA FOR THE PREPARATION OF ADVANCED BATTERY MATERIALS

1.SubstrateInducedCoagulation(SIC)inAqueousandNon-aqueousMedia

1.1.DLVOTheory

1.2.SurfaceCharging

1.3.Zeta-Potential

2.TheStabilityofAqueousandNon-aqueousDispersions

2.1.StabilityofNon-aqueousDispersions

2.2.TraceWaterinNon-aqueousDispersions

2.3.CarbonBlackDispersions

2.3.1.CarbonBlackDispersionsinPolarMedia

2.3.2.CarbonBlackDispersionsinNon-polarMedia

2.4.TitaniaandAluminaDispersions

2.4.1.TitaniaandAluminaDispersionsinPolarMedia

2.4.2.TitaniaandAluminaDispersionsinNon-polarMedia

3.AdvancedBatteryMaterials

3.1.TheCathodeMaterialLithiumCobaltOxide

3.2.HighlyConductiveCompositeElectrodes

3.3.Core-ShellCathodeMaterials

Acknowledgements

References

THE LABORATORY DIAGNOSIS OF THE PRE-PHASE OF PATHOLOGIC INTRAVASCULAR COAGULATION

Introduction

Hitherto Routine Hemostasis Tests for PIC Diagnosis

New Routine Hemostasis Tests for Diagnosis of Early PIC

IIa -Test

Ultra-specific IIa Generation Tests

Fibrinogen Function+Antigen+Ratio

Undiluted Antithrombin III Activity (AT3)

Active Endotoxin = Endotoxin Reactivity

Special Antigentic Parameters for PIC Diagnosis

NEONATAL COAGULATION PROBLEM

Introduction to Coagulation Defect in Neonatal

Platelet Defect in the Neonate

Vascular Defect in the Neonate

Coagulation Defect in the Neonate

Thrombohemostatic Defect in the Neonate

COAGULATION AND WALL SHEAR STRESS IN LIVING DONOR LIVER TRANSPLANTATION

2. Shear Stress Theory and Liver Regeneration

Following Phx

3. Concept of Immune System and Role of Shear Stress in Liver Regeneration Following Phx.

4. The Experimental and Clinical Data of Wall Shear Stress in the Liver

Experimental Data

A Comparison of the Phenotype of Cells Between the Liver and the Irrigation Solution.

Abundance of NKT Cells in the Parenchymal Space of the Liver

Clinical Data in LDLT

Changes of Thymus-Derived Cells in the Graft Liver by the Perfusion of HTK

Solution in LDLT

Changes of NKT Cells Among CD3+T Cells in the Grafts Liver by the Perfusion of HTK Solusion in LDLT

5. Shear Stress and PAI-1 During Liver Regeneration Following Phx

Flow-Induced Changes in Expression of the PAI-1 Gene in Hepatocytes

Flow-Induced Changes in the Release of PAI-1 by Hepatocytes

Shear Stress Dependency of Flow-Induced PAI-1 Expression

6. Blood Coagulation and Fibrinolytic Systems During Liver Regeneration in LDLT

Patients and Methods

Results

7. Heme Oxygenase-1 and Bilirubin Metabolism in Clinical LDLT

Materials and Methods

RESULTS

Changes in Serum Total Bilirubin Following Adult LDLT

Changes in D/T Ratio Following Adult LDLT

Correlation Between Total Bilirubin and COHB Following Adult LDLT

Augmentation of Heme Oxygenase-1 Expression in the Graft Immediately After Implantation in Adult LDLT

INDEX.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-62100-388-4

OCLC:

839302704