Circular dichroism : theory and spectroscopy / David S. Rodgers, editor.

Format:

Book

Contributor:

Rodgers, David S.

Series:

Biochemistry research trends series.

Chemical engineering methods and technology

Biochemistry research trends

Language:

English

Subjects (All):

Circular dichroism.

DNA-binding proteins.

Physical Description:

1 online resource (514 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Science Publishers, c2012.

Language Note:

English

Summary:

Circular dichroism (CD) refers to the differential absorption of left and right circularly polarised light. This phenomenon is exhibited in the absorption bands of optically active chiral molecules. CD spectroscopy has a wide range of applications in many different fields. Most notably, UV CD is used to investigate the secondary structure of proteins. This book presents current research in the study of circular dichroism, including a study of the peculiarities of the circular dichroism spectra of double-stranded DNA cholesteric liquid-crystalline dispersions; magnetic circular dichroism in electron microscopy; and, the application of CD spectroscopy for short peptides such as the human immunodeficiency virus type 1 (HIV-1) inhibitor.

Contents:

""CIRCULAR DICHROISM ""; ""CIRCULAR DICHROISM ""; ""CONTENTS ""; ""PREFACE""; ""THE CD SPECTRA OF DOUBLE-STRANDED DNA LIQUID-CRYSTALLINE DISPERSIONS ""; ""ABSTRACT ""; ""INTRODUCTION""; ""PART 1. THE DOUBLE-STRANDED DNA LIQUID CRYSTALS AND LIQUID-CRYSTALLINE DISPERSIONS ""; ""1.1. The DNA Liquid-Crystalline Phases ""; ""1.2. The Formation and Properties of the Double-Stranded DNA Liquid-Crystalline Dispersions in Polymer-Containing Water-Salt Solutions ""; ""PART 2. THE PECULIARITIES OF THE CD SPECTRA OF DOUBLE-STRANDED DNA LIQUID-CRYSTALLINE DISPERSIONS AND THEIR COMPLEXES""

""2.1. The CD Spectra of Various Types of Double-Stranded DNA Liquid-Crystalline Dispersions """"2.1.1. A Few Practically Important Consequences From the Theory ""; ""2.1.1.1. Ds DNA Molecules of Low-Molecular Mass ""; ""2.1.1.2. The New Qualitative Results ""; ""2.1.1.3. In the case of DNA CLCD with Constant D Value the Influence of Pitch (P) of the Cholesteric Helix on the Amplitude of the Band in the CD Spectrum Was Established ""; ""2.1.1.4. Structure of a Quasinematic Layer Formed by ds DNA Molecules ""

""2.2. The CD Spectra of CLCDs Formed by Double-Stranded DNA Molecules Under Various Conditions """"2.2.1. The Amplitude of the Intense Band in a CD Spectrum Depends on the Length of the ds DNA Molecules Used for Formation of CLCDs.""; ""2.2.2. The Amplitude of the Band in the CD Spectrum Depends on Properties of the Solvent, Determined by Concentration of PEG (CPEG), in a Complex Manner (Figure 16) ""; ""2.2.3. The Effectiveness of Formation of DNA CLCDs Depends on the Nature of the Cations and Not on the Nature of Anions Present In Solution [52] ""

""2.2.4. In Framework of the Above Theoretical Considerations There is a Very Important Question Regarding the Role of the Secondary Structure of Nucleic Acids in an Appearance of Intense Bands in the CD Spectra """"2.3. The CD Spectra of the CLCD Formed by ds DNA Molecules First Treated with Compounds Carrying Positively Charged Groups ""; ""2.3.1. The CD Spectra of the CLCD Formed by ds DNA Molecules First Treated with Colored Cationic Intercalator ""; ""2.3.2. The CD Spectra of the CLCD Formed by Ds DNA Molecules First Treated with Polycation ""

""PART 3. THE CD SPECTRA AT �LIQUID-RIGID� STRUCTURAL TRANSITION IN THE PARTICLES OF THE DOUBLE-STRANDED DNA CLCD """"3.1. The CD Spectra of the �Rigid� CLCDs Containing Nanobridges between Neighboring Double-Stranded DNA Molecules ""; ""3.2. The CD Spectra of the �Rigid� CLCDs Formed by (DNA-Gadolinium) Complexes ""; ""CONCLUSION ""; ""ACKNOWLEDGMENT ""; ""REFERENCES ""; ""VIBRATIONAL CIRCULAR DICHROISM STUDIES OF BIOLOGICAL MACROMOLECULES AND THEIR COMPLEXES ""; ""ABSTRACT ""; ""1. INTRODUCTION ""; ""2. ORIGIN OF VIBRATIONAL SPECTRA ""

""3. THEORETICAL BACKGROUND OF VCD SPECTROSCOPY ""

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-61209-199-7

OCLC:

923657926