Organic solvents : properties, toxicity, and industrial effects / Ryan E. Carter, editor.

Format:

Book

Contributor:

Carter, Ryan E.

Series:

Chemical engineering methods and technology.

Biotechnology in agriculture, industry and medicine series.

Chemical engineering methods and technology

Biotechnology in agriculture, industry and medicine

Language:

English

Subjects (All):

Organic solvents.

Organic compounds.

Physical Description:

1 online resource (185 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Science Publishers, c2011.

Language Note:

English

Summary:

A solvent is a liquid that becomes a solution by dissolving a solid, liquid, or gaseous solute. This book presents topical research data in the study of organic solvents, including co-solvent applications for biological systems; studying the structure of dehydrated proteins in the presence of organic solvents.

Contents:

Intro

ORGANIC SOLVENTS: PROPERTIES, TOXICITY, AND INDUSTRIAL EFFECTS

CONTENTS

PREFACE

Chapter 1 CO-SOLVENT APPLICATION FOR BIOLOGICAL SYSTEMS

ABSTRACT

1. INTRODUCTION

2. SOLVENT EFFECT OVERVIEW

APPLICATIONS OF CO-SOLVENTS

1. Enhancing Protein Stability

B. Protein Biopharmaceuticals

C. Chromatography

D. Sub-Zero Temperature Enzymology

E. Application of the Organic Solvent for NMR Studies

F. Powder Enzyme Reaction in Organic Solvent: Low Water Activity

G. Protein Precipitation

H. Virus Inactivation and Processing

Virus Inactivation

Virus and Plasmid Processing/Purification

CONCLUSION

REFERENCES

Chapter 2 LIPASE-CATALYZED SYNTHESIS OF EDIBLE SURFACTANTS IN MICROAQUEOUS ORGANIC SOLVENTS

INTRODUCTION

1. EQUILIBRIUM CONSTANT FOR LIPASE-CATALYZED CONDENSATION OF SACCHARIDE AND LAURIC ACID IN WATER-MISCIBLE ORGANIC SOLVENTS IN A BATCH REACTION

2. CONTINUOUS PRODUCTION OF ACYL ,MANNOSES BY IMMOBILIZED LIPASE USING A PACKED-BED REACTOR AND THEIR SURFACTANT PROPERTIES

3. SYNTHESES OF LAUROYL PHENOLIC GLYCOSIDES BY IMMOBILIZED LIPASE IN ORGANIC SOLVENT AND THEIR ANTIOXIDATIVE ACTIVITIES

ACKNOWLEDGMENTS

Chapter 3 ANALYSIS OF THE ORGANIC SOLVENT EFFECT ON THE STRUCTURE OF DEHYDRATED PROTEINS BY ISOTHERMAL CALORIMETRY, DIFFERENTIAL SCANNING CALORIMETRY AND FTIR SPECTROSCOPY

1. BACKGROUND AND SIGNIFICANCE

2. METHODOLOGY

2.1. FTIR Spectroscopy

2.2. Isothermal Calorimetry

2.3. Differential Scanning Calorimetry

2.4. Solubility Control

2.5. Water Content of Organic Solvents

3. DRIED PROTEINS IN ANHYDROUS ORGANIC SOLVENTS

3.1. Choice of Proteins

3.2. Choice of Organic Solvents

3.3. Solvent Hydrophilicity.

3.4. Definition of the System under Study

3.5. Analysis and Band Assignment of Protein Infrared Spectra

3.6. Interaction Enthalpies of the Dried Proteins with Organic Solvents

3.7. Effect of Solvent Hydrophilicity on the Enthalpy and Integral Absorbance Changes

3.8. The Dried Proteins in Anhydrous Organic Solvents as Studied by Differential Scanning Calorimetry

3.9. Effect of Hydrogen Bond Accepting Ability

3.10. Effect of Hydrogen Bond Donating Ability

3.11. Effect of Organic Solvents on the Structure of the Dehydrated Proteins

Chapter 4 ORGANIC-SOLVENT TOLERANT GRAM-POSITIVE BACTERIA: APPLICATIONS AND MECHANISMS OF TOLERANCE

2. PREDICTING SOLVENT TOXICITY

3. ORGANIC-SOLVENT TOLERANCE IN GRAM POSITIVE BACTERIA

3.1. Environmental Niches for Isolation of Tolerant Bacteria

3.2. Bacterial Mechanisms of Tolerance and Adaptation to Organic Solvents

3.2.1. Biodegradation of Toxic Compounds

3.2.2. Adaptation by Cell Wall and Membrane Modifications

3.2.2.1. Fatty Acid Composition

3.2.2.2. Mycolic Acid Composition

3.2.3. Efflux Pumps and other Mechanisms

CONCLUSIONS

Chapter 5 TOXICITY OF ORGANIC SOLVENTS AND IONIC LIQUIDS TO LACTIC ACID-PRODUCING MICROBES

1. TOXICITY OF ORGANIC SOLVENTS TO LACTIC ACID-PRODUCING MICROBES

2. TOXICITY OF IMIDAZOLIUM-BASED IONIC LIQUIDS ON LACTIC ACID-PRODUCING BACTERIA

3. GREENNESS OF IONIC LIQUIDS AS AN ALTERNATIVE SOLVENT

Chapter 6 EFFECT OF HYDROGEN BOND ACCEPTING ORGANIC SOLVENTS ON THE BINDING OF COMPETITIVE INHIBITOR AND STORAGE STABILITY OF -CHYMOTRYPSIN1

1. BACKGROUND AND SIGNIFICANCE.

2. BINDING OF THE COMPETITIVE INHIBITOR PROFLAVIN AND THE STORAGE STABILITY OF -CHYMOTRYPSIN IN ORGANIC SOLVENTS

2.1. Choice of Organic Solvents

2.2. Thermodynamic Activity of Water in Organic Solvents

2.3. Binding of Proflavin in Water

2.4. Spectra of Proflavin in Water-Organic Mixtures

2.5. Binding of Proflavin in Organic Solvents

2.6. Enzyme Storage Stability

2.7. The State of Hydrogen Bond Network of Water in Hydrogen Bond Accepting Organic Solvents as Studied By FTIR Spectroscopy

2.8. Excess Partial Molar Quantities of Water and Organic Solvents

2.9. Effect of Organic Solvents on Storage Stability and Binding of Competitive Inhibitor

Chapter 7 REGULARITIES OF ORGANIC SOLVENTS PENETRATION INTO TETRAFLUOROETHYLENE-PROPYLENE COPOLYMER1

INDEX.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record and CIP data provided by publisher.

ISBN:

1-61122-229-X

OCLC:

831625640