Practical functional group synthesis / Robert A. Stockland, Jr.

Format:

Book

Author/Creator:

Stockland, Robert, Jr., 1971- author.

Language:

English

Subjects (All):

Chemical bonds.

Functional groups.

Chemistry, Organic.

Physical Description:

1 online resource (700 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, New Jersey : Wiley, 2016.

Language Note:

English

Summary:

A practical handbook for chemists performing bond forming reactions, this book features useful information on the synthesis of common functional groups in organic chemistry. •Details modern functional group synthesis through carbon-heteroelement (N, O, P, S, B, halogen) bond forming reactions with a focus on operational simplicity and sustainability. •Summarizes key and recent developments - which are otherwise scattered across journal literature - into a single source •Contains over 100 detailed preparations of common functional groups •Included 25 troubleshooting guides with suggestions and potential solutions to common problems. •Complements the text in enhanced ebook editions with tutorial videos where the author provides an introduction to microwave assisted chemistry

Contents:

Intro

Title Page

Copyright Page

Contents

Preface

Acknowledgments

Chapter 1 INTRODUCTION TO PRACTICAL FUNCTIONAL GROUP SYNTHESIS

1.1 GENERAL APPROACHES FOR DESIGNING SYNTHESES

1.2 NEW VERSIONS OF "CLASSIC" ORGANIC REACTIONS

1.3 SOLVENT SELECTION AND SOLVENT-FREE REACTIONS

1.4 OPERATIONAL SIMPLICITY

1.5 METAL-CATALYZED TRANSFORMATIONS

1.6 ORGANOCATALYSIS

1.7 MICROWAVE- AND ULTRASOUND-ASSISTED CHEMISTRY

1.7.1 General Checklist for Performing a Microwave-Assisted Reaction

1.8 SUSTAINABILITY

1.9 ASYMMETRIC SYNTHESIS

REFERENCES

Chapter 2 PREPARATION OF ALCOHOLS, ETHERS, AND RELATED COMPOUNDS

2.1 PREPARATION OF ALCOHOLS, ETHERS, AND RELATED COMPOUNDS THROUGH THE FORMATION OF OXYGEN-CARBON(sp3) BONDS

2.1.1 Troubleshooting the Preparation of Alcohols, Ethers, and Related Compounds

2.2 PREPARATION OF PHENOLS, ARYL ETHERS, AND RELATED COMPOUNDS THROUGH THE FORMATION OF OXYGEN-CARBON(sp2) BONDS

2.2.1 Troubleshooting the Preparation of Phenols, Aryl Ethers, and Related Compounds

2.3 PREPARATION OF VINYL ETHERS AND RELATED COMPOUNDS THROUGH THE FORMATION OF OXYGEN-CARBON(sp2) BONDS

2.3.1 Troubleshooting the Preparation of Vinyl Ethers and Related Compounds

2.4 PREPARATION OF ALKYNYL ETHERS AND RELATED COMPOUNDS THROUGH THE FORMATION OF OXYGEN-CARBON(sp) BONDS

2.4.1 Troubleshooting the Preparation of Alkynyl Ethers and Related Compounds

Chapter 3 SYNTHESIS OF AMINES, AMIDES, AND RELATED COMPOUNDS

ALKYLAMINES

3.1 SYNTHESIS OF ALKYLAMINES AND RELATED COMPOUNDS THROUGH NITROGEN-CARBON(sp3) BOND-FORMING REACTIONS

3.1.1 Troubleshooting the Synthesis of Alkylamines and Related Compounds

3.2 SYNTHESIS OF ARYLAMINES AND RELATED COMPOUNDS THROUGH NITROGEN-CARBON(sp2) BOND-FORMING REACTIONS

3.2.1 Troubleshooting the Synthesis of Arylamines and Related Compounds.

3.3 SYNTHESIS OF VINYLAMINES AND RELATED COMPOUNDS THROUGH NITROGEN-CARBON(sp2) BOND-FORMING REACTIONS

3.3.1 Troubleshooting the Synthesis of Vinylamines and Related Compounds

3.4 SYNTHESIS OF YNAMIDES AND RELATED COMPOUNDS THROUGH NITROGEN-CARBON(sp) BOND-FORMING REACTIONS

3.4.1 Troubleshooting the Synthesis of Ynamines and Ynamides

Chapter 4 SYNTHESIS OF ORGANOPHOSPHINES, PHOSPHONATES, AND RELATED COMPOUNDS

4.1 Introduction to the Synthesis of Organophosphorus Compounds Generated THROUGH THE FORMATION OF PHOSPHORUS-CARBON BONDS

4.2 SYNTHESIS OF ALKYLPHOSPHINES AND RELATED COMPOUNDS THROUGH THE FORMATION OF PHOSPHORUS-CARBON(sp3) BONDS

4.2.1 Troubleshooting the Synthesis of Alkylphosphines and Related Compounds

4.3 SYNTHESIS OF ARYLPHOSPHINES AND RELATED COMPOUNDS THROUGH THE FORMATION OF PHOSPHORUS-CARBON(sp2) BONDS

4.3.1 Troubleshooting the Synthesis of Arylphosphines and Related Compounds

4.4 SYNTHESIS OF VINYLPHOSPHINES AND RELATED COMPOUNDS THROUGH THE FORMATION OF PHOSPHORUS-CARBON(sp2) BONDS

4.4.1 Troubleshooting the Synthesis of Vinylphosphines and Related Compounds

4.5 SYNTHESIS OF ALKYNYLPHOSPHINES AND RELATED COMPOUNDS THROUGH THE FORMATION OF PHOSPHORUS-CARBON(sp) BONDS

4.5.1 Troubleshooting the Synthesis of Alkynylphosphines and Related Compounds

Chapter 5 SYNTHESIS OF THIOETHERS, SULFONES, AND RELATED COMPOUNDS

5.1 SYNTHESIS OF THIOETHERS AND RELATED COMPOUNDS THROUGH THE FORMATION OF SULFUR-CARBON(sp3) BONDS

5.1.1 Troubleshooting the Synthesis of Thioethers and Related Compounds

5.2 SYNTHESIS OF Aryl THIOETHERS AND RELATED COMPOUNDS THROUGH THE FORMATION OF SULFUR-CARBON(sp2) BONDS

5.2.1 Troubleshooting the Synthesis of Thioethers and Related Compounds.

5.3 SYNTHESIS OF Vinyl THIOETHERS AND RELATED COMPOUNDS THROUGH THE FORMATION OF SULFUR-CARBON(sp2) BONDS

5.3.1 Troubleshooting the Synthesis of Vinyl Sulfides and Related Compounds

5.4 SYNTHESIS OF THIOETHERS AND RELATED COMPOUNDS THROUGH THE FORMATION OF SULFUR-CARBON(sp) BONDS

5.4.1 Troubleshooting the Synthesis of Alkynyl Thioethers and Related Compounds

Chapter 6 SYNTHESIS OF ORGANOBORONIC ACIDS, ORGANOBORONATES, AND RELATED COMPOUNDS

6.1 SYNTHESIS OF ALKYLBORONATES AND RELATED COMPOUNDS THROUGH THE FORMATION OF BORON-CARBON(sp3) BONDS

6.1.1 Troubleshooting the Synthesis of Alkylboronates and Related Compounds

6.2 SYNTHESIS OF ARYLBORONATES AND RELATED COMPOUNDS THROUGH THE FORMATION OF BORON-CARBON(sp2) BONDS

6.2.1 Troubleshooting the Synthesis of Arylboronates and Related Compounds

6.3 SYNTHESIS OF VINYLBORONATES AND RELATED COMPOUNDS THROUGH THE FORMATION OF BORON-CARBON(sp2) BONDS

6.3.1 Troubleshooting the Synthesis of Vinylboronates and Related Compounds

6.4 SYNTHESIS OF ALKYNYLBORONATES AND RELATED COMPOUNDS THROUGH THE FORMATION OF BORON-CARBON(sp) BONDS

6.4.1 Troubleshooting the Synthesis of Alkynylboronates and Related Compounds

Chapter 7 SYNTHESIS OF ORGANOHALIDES

7.1 SYNTHESIS OF ALKYL HALIDES THROUGH THE FORMATION OF HALOGEN-CARBON(sp3) BONDS

7.1.1 Troubleshooting the Synthesis of Alkyl Halides and Related Compounds

7.2 SYNTHESIS OF ARYL HALIDES THROUGH THE FORMATION OF HALOGEN-CARBON(sp2) BONDS

7.2.1 Troubleshooting the Synthesis of Aryl Halides and Related Compounds

7.3 SYNTHESIS OF VINYL HALIDES THROUGH THE FORMATION OF HALOGEN-CARBON(sp2) BONDS

7.3.1 Troubleshooting the Synthesis of Vinyl Halides and Related Compounds

7.4 SYNTHESIS OF ALKYNYL HALIDES THROUGH THE FORMATION OF HALOGEN-CARBON(sp) BONDS.

7.4.1 Troubleshooting the Synthesis of Alkynyl Halides and Related Compounds

Index

EULA.

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

9781119015772

1119015774

9781119015840

1119015847

OCLC:

935251534