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Clinical trials in older people / edited by Antonio Cherubini [and five others] ; contributors Heather Allore [and thirty five others].
- Format:
- Book
- Language:
- English
- Subjects (All):
- Clinical trials.
- Gerontology--Research.
- Gerontology.
- Physical Description:
- 1 online resource (308 p.)
- Edition:
- 1st ed.
- Place of Publication:
- Chichester, England : Wiley Blackwell, 2015.
- Language Note:
- English
- Summary:
- Clinical Trials in Older Adults is the first book to consider the methodological issues underlying the evaluation of new treatments in older people. * Provides information on the methodology, monitoring and regulations for those planning to conduct a clinical trials involving older adults * Contains examples of ongoing trials involving older adults, and presents the main characteristics of many recently published * Depicts how the issues regarding older adults in clinical trials could be properly addressed with the appropriate study design and conduct * Identifies key issues in performing clinical trials in older patients with common geriatric conditions, i.e. Alzheimer's dementia, depression, low muscle mass, cancer
- Contents:
- The exclusion of older subjects from clinical trials : the predict study / Antonio Cherubini, Peter Crome
- Clinical trials in older adults : a point of view from the industry / Susanna Del Signore, Philippe Guillet
- Ethical issues in clinical trials involving older subjects : the right to participate in clinical trials and have access to care; the protection of vulnerable subjects and the issue of informed consent / Emmanuel Hirsch, Paul-Loup Weil-Dubuc
- Mastering the design of clinical trials for older persons : the tension between external validity and feasibility / Luigi Ferrucci, Stephanie Studenski
- Pharmacokinetic and pharmacodynamic studies in older adults / Arduino A Mangoni, Paul AF Jansen, Stephen H.D. Jackson
- The role of comprehensive geriatric assessment of older adults in clinical studies / Graziano Onder, Agnese Collamati, Andrea Poscia, Roberto Bernabei
- Statistical issues in designing and interpreting clinical trials in older adults / Heather Allore, Mark A. Espeland, Michael E. Miller
- Challenges in implementing large-scale clinical trials in moderately functioning older adults / Stephen D. Anton, Sandrine Sourdet, Marco Pahor, & Todd Manini
- Clinical trials in Alzheimer's disease / Julien Delrieu , Bruno Vellas
- Clinical trials in late-life mood disorders / Lucio Ghio, Werner Natta, Marco Vaggi, Luigi Ferrannini
- Clinical trials for conditions of low muscle mass and strength / Stephanie Studenski, Rosaly Correa-de-Araujo and Luigi Ferrucci
- Clinical trials of cancer treatment in the elderly / Lodovico Balducci, Iordanis Gravanis, Francesco Pignatti
- Clinical trials in nursing homes : challenges and practical solutions / Sandra Simmons, Barbara Resnik, John Schnelle, Joe Ouslander.
- Notes:
- Description based upon print version of record.
- Includes bibliographical references at the end of each chapters and index.
- Description based on print version record.
- ISBN:
- 9781118323489
- 1118323483
- 9781118323434
- 1118323432
- 9781118323472
- 1118323475
- OCLC:
- 935920174
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