Handbook of polymers for pharmaceutical technologies. Volume 2, Processing and applications / edited by Vijay Kumar Thakur and Manju Kumari Thakur.

Format:

Book

Contributor:

Thakur, Manju Kumari, editor.

Thakur, Vijay Kumar, 1981- editor.

Language:

English

Subjects (All):

Polymers in medicine.

Pharmaceutical technology.

Physical Description:

1 online resource (490 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, New Jersey ; Salem, Massachusetts : John Wiley & Sons : Scrivener Publishing LLC, 2015.

Language Note:

English

Summary:

Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications. Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry, Volume 2: Processing and Applications, Volume 3: Biodegradable Polymers, Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers.

Contents:

Cover; Title Page; Copyright Page; Dedication; Contents; Preface; 1 Particle Engineering of Polymers into Multifunctional Interactive Excipients; 1.1 Introduction; 1.2 Polymers as Excipients; 1.3 Material Properties Affecting Binder Activity; 1.3.1 Particle Size; 1.3.2 Deformation Mechanisms; 1.3.3 Glass Transition Temperature (Tg); 1.4 Strategies for Improving Polymeric Filler-Binder Performance for Direct Compression; 1.4.1 Interactive Mixing; 1.4.2 Challenges to Interactive Mixing; 1.4.3 Controlling Interparticle Cohesion; 1.5 Preparation and Characterization of Interactive Excipients

1.5.1 Particle Size and Size Distribution of Excipients1.5.2 Effect of L-leucine on Surface Morphology; 1.5.3 Effect of L-leucine on Surface Composition; 1.5.4 Effect of L-leucine on Surface Energy; 1.5.5 Effect of L-leucine on Interparticle Cohesion; 1.6 Performance of Interactive Excipients; 1.6.1 Blending Ability; 1.6.2 Effect on Flow; 1.6.3 Binder Activity; 1.7 Investigation of the Effect of Polymer Mechanical Properties; 1.8 Conclusion; References; 2 The Art of Making Polymeric Membranes; 2.1 Introduction; 2.2 Types of Membranes; 2.2.1 Porous Membranes; 2.2.2 Nonporous Membranes

2.2.3 Liquid Membranes (Carrier Mediated Transport)2.2.4 Asymmetric Membranes; 2.3 Preparation of Membranes; 2.3.1 Phase Inversion/Separation; 2.3.2 Vapor-Induced Phase Separation (VIPS); 2.3.3 Thermally-Induced Phase Separation (TIPS); 2.3.4 Immersion Precipitation; 2.3.5 Film/Dry Casting Technique; 2.3.6 Track Etching; 2.3.7 Electrospinning; 2.3.7.1 Preparation of Electrospun Nanofiber Membranes (ENMs) with Single Component; 2.3.7.2 Preparation of Nanofibers with Two Side-by-Side Components; 2.3.7.3 Preparation of Core-Sheath and Hollow Nanofibers; 2.3.8 Spraying; 2.3.9 Foaming

2.3.10 Particle Leaching2.3.11 Precipitation from the Vapor Phase; 2.3.12 Emulsion Freeze-Drying; 2.3.13 Sintering; 2.3.14 Stretching; 2.3.15 Composite/Supported; 2.3.16 Mixed Matrix Membranes (MMMs); 2.3.17 Hollow Fiber Membranes; 2.3.17.1 Methods for Spinning; 2.3.18 Metal-Organic Frameworks (MOFs); 2.4 Modification of Membranes; 2.4.1 Modification of Polymeric Membrane by Additives/Blending; 2.4.2 Coating; 2.4.3 Surface Modification by Chemical Reaction; 2.4.4 Interfacial Polymerization (IP)/Copolymerization; 2.4.5 Plasma Polymerization/Treatment

2.4.6 Surface Modification by Irradiation of High Energy Particles2.4.7 UV Irradiation; 2.4.8 Ion-Beam Irradiation; 2.4.9 Surface Modification by Heat Treatment; 2.4.10 Graft Polymerization/Grafting; 2.4.11 Other Techniques; 2.5 Characterization of Membrane by Different Techniques; 2.5.1 Conventional Physical Methods to Determine Pore Size and Pore Size Distribution; 2.5.1.1 Bubble Gas Transport Method; 2.5.1.2 Mercury Intrusion Porosimetry; 2.5.1.3 Gas Liquid Equilibrium Method (Permporometry); 2.5.1.4 Adsorption-Desorption Method: Barett-Joyner-Halenda (BJH) Method

2.5.1.5 Permeability Methods

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on online resource; title from PDF title page (ebrary, viewed August 06, 2015).

ISBN:

9781119041399

1119041392

9781119041412

1119041414

9781119041405

1119041406

OCLC:

921259137