Esophageal cancer and Barrett's esophagus / Prateek Sharma, Richard Sampliner, David Ilson.

Format:

Book

Author/Creator:

Sharma, Prateek, author.

Sampliner, Richard E., author.

Ilson, David (David H.), author.

Standardized Title:

Barrett's esophagus and esophageal adenocarcinoma.

Language:

English

Subjects (All):

Esophagus--Cancer.

Esophagus.

Physical Description:

1 online resource (313 p.)

Edition:

Third edition.

Place of Publication:

Chichester, West Sussex, [England] : Wiley Blackwell, 2015.

Language Note:

English

Summary:

Esophageal Cancer and Barrett's Esophagus, 3E, focuses on these two common and key conditions that affect the esophagus, providing expert guidance to their pathogenesis, cause, prevention, diagnosis and clinical management. Top international names in the field examine each of the many issues involved, using the very latest evidence-based research, and clear, didactic adviceallows the reader to understand the best methods of diagnosis and clinical management of each condition - whether early or late stage. Well-illustrated and fully revised to include the latest in ACG/ASG/UEGW guidelines, itis the perfect consultation tool for gastroenterologists and oncologists managing patients with cancer of the esophagus. It is also ideal for teaching residents and fellows optimum patient management, and for identifying areas requiring future research.

Contents:

Cover; Title Page; Copyright; Contents; List of contributors; Preface; Chapter 1 Epidemiology of esophageal carcinoma; 1.1 The incidence and mortality related to esophageal cancer; 1.2 Mortality; 1.3 Risk factors for EA; Chapter 2 Barrett's esophagus: definition and diagnosis; 2.1 Introduction; 2.2 Early history of Barrett's esophagus; 2.3 Early reports on the histology of Barrett's esophagus; 2.4 Identification of the gastroesophageal junction; 2.5 Recognition of short segment Barrett's esophagus; 2.6 Intestinal metaplasia and adenocarcinoma of the esophagus

2.7 The problem of cardiac mucosa2.8 Definition of Barrett's esophagus; 2.9 Diagnostic criteria for Barrett's esophagus; 2.10 Intestinal metaplasia at the GEJ; Chapter 3 Epidemiology and prevalence of Barrett's esophagus; 3.1 Introduction; 3.2 BE prevalence; 3.3 BE incidence; 3.4 Etiology and risk factors for BE; 3.5 Neoplastic progression risk in BE; 3.6 Conclusions; Chapter 4 Esophageal adenocarcinoma: risk factors; 4.1 Introduction; 4.2 Gastroesophageal reflux disease (GERD); 4.3 Barrett's esophagus (BE); 4.4 Obesity; 4.5 Smoking; 4.6 Alcohol; 4.7 Dietary factors; 4.8 Medication use

4.9 H. pylori4.10 Demographics; 4.11 Summary; Chapter 5 Esophageal motility abnormalities in Barrett's esophagus; 5.1 Introduction; 5.2 Antireflux barrier; 5.3 Lower esophageal sphincter; 5.4 Diaphragmatic sphincter and hiatal hernia; 5.5 Mechanical properties of the relaxed EGJ; 5.6 Esophageal clearance; 5.7 Peristaltic dysfunction; 5.8 Gastric emptying and duodenogastroesophageal reflux; 5.9 Therapy of motor abnormalities in Barrett's esophagus; 5.10 Conclusion; Chapter 6 Molecular biology of Barrett's esophagus and esophageal adenocarcinoma; 6.1 Introduction

6.2 Genetic and host susceptibility6.3 Environmental factors contributing to the development of BE; 6.4 Genomic instability mutations and copy number changes in candidate genes; 6.5 The advent of next generation sequencing; 6.6 Future directions and conclusions; Chapter 7 Histology of Barrett's esophagus: metaplasia and dysplasia; 7.1 Introduction; 7.2 Normal anatomy and histology; 7.3 Histology of Barrett's esophagus; 7.4 Intestinal metaplasia of the EGJ; 7.5 Barrett's esophagus-related dysplasia; 7.6 Intramucosal adenocarcinoma (IMC); 7.7 Submucosal adenocarcinoma

7.8 Morphologic types of dysplasia7.9 Sampling error and observer variation in Barrett's esophagus-related dysplasia; 7.10 Surrogate biomarkers for assessing risk of esophageal adenocarcinoma; Chapter 8 Helicobacter pylori and esophageal neoplasia; 8.1 Introduction; 8.2 H. pylori infection - gastritis pattern and gastric physiology with impact on gastroesophageal reflux disease; 8.3 Epidemiological studies - GERD symptoms, erosive esophagitis and H. pylori; 8.4 H. pylori, Barrett's esophagus and esophageal adenocarcinoma; 8.5 H. pylori eradication and GERD

8.6 H. pylori and esophageal squamous cell carcinoma

Notes:

Preceded by Barrett's esophagus and esophageal adenocarcinoma / edited by Prateek Sharma, Richard Sampliner. 2nd ed. 2006.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

9781118655153

111865515X

9781118655184

1118655184

9781118655191

1118655192

OCLC:

904400113