Handbook of GC-MS : fundamentals and applications / Hans-Joachim Hübschmann.

Format:

Book

Author/Creator:

Hübschmann, Hans-Joachim, author.

Language:

English

Subjects (All):

Gas chromatography.

Mass spectrometry.

Physical Description:

1 online resource (882 p.)

Edition:

Third edition.

Place of Publication:

Weinheim, Germany : Wiley-VCH, 2015.

Language Note:

English

Summary:

The only comprehensive reference on this popular and rapidly developing technique provides a detailed overview, ranging from fundamentals to applications, including a section on the evaluation of GC-MS analyses. As such, it covers all aspects, including the theory and principles, as well as a broad range of real-life examples taken from laboratories in environmental, food, pharmaceutical and clinical analysis. It also features a glossary of approximately 300 terms and a substance index that facilitates finding a specific application. For this new edition the work has been now extended to two

Contents:

Cover; Title Page; Copyright; Dedication; Contents; Foreword; Preface to the Third Edition; Chapter 1 Introduction; 1.1 The Historical Development of the GC-MS Technique; Chapter 2 Fundamentals; 2.1 Sample Preparation; 2.1.1 Solid Phase Extraction; 2.1.2 Solid Phase Microextraction; 2.1.3 Pressurized Liquid Extraction; 2.1.3.1 In-Cell Sample Preparation; 2.1.3.2 In-Cell Moisture Removal; 2.1.3.3 In-Cell Hydrocarbon Oxidation; 2.1.4 Online Liquid Chromatography Clean-Up; 2.1.5 Headspace Techniques; 2.1.5.1 Static Headspace Technique; 2.1.5.2 Dynamic Headspace Technique (Purge and Trap)

2.1.5.3 Coupling of Purge and Trap with GC-MS Systems 2.1.5.4 Headspace versus Purge and Trap; 2.1.6 Adsorptive Enrichment and Thermal Desorption; 2.1.6.1 Sample Collection; 2.1.6.2 Calibration; 2.1.6.3 Desorption; 2.1.7 Pyrolysis; 2.1.7.1 Foil Pyrolysis; 2.1.7.2 Curie Point Pyrolysis; 2.1.7.3 Micro-furnace Pyrolysis; 2.1.8 Thermal Extraction (Outgassing); 2.1.9 QuEChERS Sample Preparation; 2.2 Gas Chromatography; 2.2.1 Sample Inlet Systems; 2.2.2 Carrier Gas Regulation; 2.2.2.1 Forward Pressure Regulation; 2.2.2.2 Back Pressure Regulation; 2.2.2.3 Carrier Gas Saving

2.2.3 Injection Port Septa 2.2.3.1 Septum Purge; 2.2.3.2 The Micro Seal Septum; 2.2.4 Injection Port Liner; 2.2.4.1 Split Injection; 2.2.4.2 Splitless Injection; 2.2.4.3 Liner Activity and Deactivation; 2.2.4.4 Liner Geometry; 2.2.5 Vaporizing Sample Injection Techniques; 2.2.5.1 Hot Needle Thermo Spray Injection Technique; 2.2.5.2 Cold Needle Liquid Band Injection Technique; 2.2.5.3 Filled Needle Injections; 2.2.5.4 Split Injection; 2.2.5.5 Splitless Injection (Total Sample Transfer); 2.2.5.6 Concurrent Solvent Recondensation; 2.2.5.7 Concurrent Backflush

2.2.6 Temperature Programmable Injection Systems 2.2.6.1 The PTV Cold Injection System; 2.2.6.2 The PTV Injection Procedures; 2.2.6.3 On-Column Injection; 2.2.6.4 PTV On-Column Injection; 2.2.6.5 Cryofocussing; 2.2.6.6 PTV Cryo-Enrichment; 2.2.7 Capillary Column Choice and Separation Optimization; 2.2.7.1 Sample Capacity; 2.2.7.2 Internal Diameter; 2.2.7.3 Film Thickness; 2.2.7.4 Column Length; 2.2.7.5 Setting the Carrier Gas Flow; 2.2.7.6 Properties of Column Phases; 2.2.7.7 Properties of Ionic Liquid Phases; 2.2.8 Chromatography Parameters; 2.2.8.1 The Chromatogram and Its Meaning

2.2.8.2 Capacity Factor k' 2.2.8.3 Chromatographic Resolution; 2.2.8.4 Factors Affecting the Resolution; 2.2.8.5 Maximum Sample Capacity; 2.2.8.6 Peak Symmetry; 2.2.8.7 Optimization of Carrier Gas Flow; 2.2.8.8 Effect of Oven Temperature Ramp Rate; 2.2.9 Fast Gas Chromatography Solutions; 2.2.9.1 Fast Chromatography; 2.2.9.2 Ultra-Fast Chromatography; 2.2.10 Multi-Dimensional Gas Chromatography; 2.2.10.1 Heart Cutting; 2.2.10.2 Comprehensive GC - GC x GC; 2.2.10.3 Modulation; 2.2.10.4 Detection; 2.2.10.5 Data Handling; 2.2.10.6 Moving Capillary Stream Switching

2.2.11 Classical Detectors for GC-MS Systems

Notes:

Description based upon print version of record.

Includes bibliographical references and index at the end of each chapters.

Description based on online resource; title from PDF title page (ebrary, viewed May 12, 2015).

ISBN:

9783527674329

3527674322

9783527674305

3527674306

OCLC:

908520023