Radiochemical syntheses : further radiopharmaceuticals for positron emission tomography and new strategies for their production / edited by Peter J. H. Scott.

Format:

Book

Contributor:

Scott, Peter J. H., editor.

Series:

Radiochemical syntheses ; Volume 2.

Radiochemical Syntheses ; Volume 2

Language:

English

Subjects (All):

Radiopharmaceuticals--Synthesis.

Radiopharmaceuticals.

Tomography, Emission.

Physical Description:

1 online resource (280 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, New Jersey : Wiley, 2015.

Summary:

This book describes methods and procedures for preparing PET radiopharmaceuticals, and highlights new methods for conducting radiochemical reactions with carbon-11 (C11) and fluorine-18 (F18), which are two of the most commonly used radionuclides in positron emission tomography (PET) imaging. Provides reliable methods for radiochemical syntheses and reactions, including all essential information to duplicate the procedure; Eliminates the time-consuming process of searching journal articles and extracting pertinent details from lengthy experimental sections or supporting information

Contents:

Title Page; Copyright Page; Contents; Radiochemical Syntheses; Contributors; Editorial Preface; Abbreviations; PART I FLUORINE-18 LABELED RADIOPHARMACEUTICALS; Chapter 1 Synthesis of (2212;)-[18F]Flubatine ([18F]FLBT); 1 INTRODUCTION; 2 SYNTHESIS PROCEDURES; 3 QUALITY CONTROL PROCEDURES; WASTE DISPOSAL INFORMATION; CHEMICAL ABSTRACTS NOMENCLATURE (REGISTRY NUMBER); REFERENCES AND NOTES; Chapter 2 Synthesis of [18F]-(2212;)Fluoroethoxy Benzovesamicol ([18F]FEOBV); 1 INTRODUCTION; 2 SYNTHESIS PROCEDURES; 3 QC PROCEDURES; WASTE DISPOSAL INFORMATION; CHEMICAL ABSTRACTS NOMENCLATURE (REGISTRY NUMBER)

REFERENCES AND NOTES Chapter 3 Synthesis of [18F] Fluoromethylcholine ([18F]FCH) via [18F] Fluoromethyl Tosylate; 1 INTRODUCTION; 2 SYNTHESIS PROCEDURES; 3 QUALITY CONTROL; WASTE DISPOSAL INFORMATION; CHEMICAL ABSTRACTS NOMENCLATURE (REGISTRY NUMBER); REFERENCES AND NOTES; Chapter 4 Radiosynthesis of [18F] Flotegatide ([18F]RGD-K5); 1 INTRODUCTION; 2 SYNTHESIS PROCEDURES; 3 QUALITY CONTROL PROCEDURES; WASTE DISPOSAL INFORMATION; CHEMICAL ABSTRACTS NOMENCLATURE (REGISTRY NUMBER); REFERENCES AND NOTES; Chapter 5 Synthesis of 3-[18F]Fluoro-5-(2-Pyridinylethynyl)Benzonitrile ([18F]FPEB)

1 INTRODUCTION2 SYNTHESIS PROCEDURES; 3 QUALITY CONTROL PROCEDURES; WASTE DISPOSAL INFORMATION; CHEMICAL ABSTRACT NOMENCLATURE (REGISTRY NUMBER); REFERENCES AND NOTES; Chapter 6 Radiosynthesis of 2'-Deoxy-2'-[18F] Fluoro-5-Methyl- 1-β-d-Arabinofuranosyluracil ([18F]FMAU); 1 INTRODUCTION; 2 SYNTHESIS PROCEDURES; 3 QC PROCEDURES; WASTE DISPOSAL INFORMATION; CHEMICAL ABSTRACTS NOMENCLATURE (REGISTRY NUMBER); REFERENCES AND NOTES; PART II CARBON-11 LABELED RADIOPHARMACEUTICALS; Chapter 7 Synthesis of N-[11C]Methyl-4-Piperidinyl Propionate ([11C]PMP); 1 INTRODUCTION; 2 SYNTHESIS PROCEDURES

3 QUALITY CONTROL PROCEDURES WASTE DISPOSAL INFORMATION; REFERENCES AND NOTES; Chapter 8 Synthesis of 1-(2,4-Dichlorophenyl)-4-Cyano-5-(4-[11C]methoxyphenyl)-N-(Piperidin-1-yl)-1H-Pyrazole-3-Carboxamide ([11C]OMAR); 1 INTRODUCTION; 2 SYNTHESIS PROCEDURES; 3 QC PROCEDURES; WASTE DISPOSAL INFORMATION; CHEMICAL ABSTRACTS NOMENCLATURE (REGISTRY NUMBER); REFERENCES AND NOTES; Chapter 9 Synthesis of Carbon-11 Labeled (+)-4-Propyl-3,4,4a,5,6, 10b-Hexahydro-2H-Naphtho[1,2-B][1,4]Oxazin-9-Ol ([11C]-(+)-PHNO); 1 INTRODUCTION; 2 SYNTHETIC PROCEDURES; 3 QUALITY CONTROL PROCEDURES

WASTE DISPOSAL INFORMATION CHEMICAL ABSTRACTS NOMENCLATURE (REGISTRY NUMBER); REFERENCES AND NOTES; Chapter 10 Synthesis of (R)-[N-Methyl-11C]PK11195; 1 INTRODUCTION; 2 SYNTHESIS PROCEDURES; 3 QUALITY CONTROL PROCEDURES; WASTE DISPOSAL INFORMATION; CHEMICAL ABSTRACTS NOMENCLATURE (REGISTRY NUMBER); REFERENCES AND NOTES; PART III OTHER RADIOPHARMACEUTICALS; Chapter 11 Synthesis of Oxygen-15 Water ([15O]H2O); 1 INTRODUCTION; 2 SYNTHESIS PROCEDURES; 3 QC PROCEDURES; WASTE DISPOSAL INFORMATION; CHEMICAL ABSTRACTS NOMENCLATURE (REGISTRY NUMBER); REFERENCES AND NOTES

PART IV NEW METHODS FOR THE SYNTHESIS AND QUALITY CONTROL OF RADIOPHARMACEUTICALS

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

9781118834046

1118834046

9781118834114

1118834119

9781118834008

1118834003

OCLC:

900565387