Clinical guide to transplantation in lymphoma / edited by Bipin N. Savani, MD, Mohamad Mohty, MD, PhD.

Format:

Book

Contributor:

Savani, Bipin N., editor.

Mohty, Mohamad, editor.

Language:

English

Subjects (All):

Lymphomas--Surgery.

Lymphomas.

Stem cells--Transplantation.

Stem cells.

Physical Description:

1 online resource (288 p.)

Edition:

1st ed.

Place of Publication:

Chichester, [England] : Wiley Blackwell, 2015.

Language Note:

English

Summary:

The first book on clinical guide to transplantation in lymphoma to present cutting edge knowledge on how to integrate, transplantation and novel therapies in patients with lymphoid malignancies * Provides practical management guidance on how to integrate, transplantation and novel therapies in patients with lymphoid malignancies * Covers an overview of transplantation in lymphoma, and management of the lymphoid malignancies * Discusses organizational aspects of transplant patients and managing a transplant program * Appendices provide practical quick-reference information on follow-up after autologous and allogenic stem cell transplantation in lymphoma

Contents:

Title page; Copyright page; Contents; List of contributors; Foreword; Introduction; Declaration of commercial interest; References; Section 1 Transplantation in lymphomas; Chapter 1 Lymphoma and transplantation: historical perspective; Brief history of hematopoietic cell transplantation; History of autologous HCT in non-Hodgkin lymphoma; History of autologous HCT in Hodgkin lymphoma; History of allogeneic HCT in lymphoma; General historical considerations; References; Chapter 2 Lymphoma: working committee and data reporting after transplantation in lymphoma; Introduction; Registry structure

Working committees Data reporting; Overcoming challenges to data reporting; Flow of data; Data quality; The Lymphoma Working Committee; Statistical methods; Type of data; Intervals and patient selection; Unadjusted comparison; Adjusted comparison; Selected examples from the CIBMTR Lymphoma Committee; Value for young investigators; Value for public and other stakeholders; Conclusion; References; Chapter 3 Use of transplantation in lymphoma: adults; Introduction; Hodgkin lymphoma; Non-Hodgkin lymphoma; Diffuse large B-cell lymphoma; Follicular lymphoma; Histologic transformation to DLBCL

Mantle cell lymphoma Burkitt lymphoma; Primary CNS lymphoma; Peripheral T-cell lymphoma; Prognostic tools; Maintenance therapies; Novel therapies; Conclusions; References; Chapter 4 Hematopoietic stem cell transplantation for lymphoma in children, adolescents, and young adults; Introduction; Principles of autologous and allogeneic HSCT in pediatric lymphomas; Hodgkin lymphoma; Lymphoblastic lymphoma; Anaplastic large-cell lymphoma; Mature B-cell lymphomas: Burkitt lymphoma, diffuse large B-cell lymphoma, and primary mediastinal B-cell lymphoma; Future directions; Conclusions; References

Chapter 5 Preparative regimens for lymphoma: autologous hematopoietic stem cell transplantation Rationale for chemotherapy dose intensification for disease eradication; Traditional preparative regimens; Incorporation of monoclonal antibodies in autologous HCT preparative regimens; Rituximab; Monoclonal antibodies conjugated to radionuclide; Novel agents used in preparative regimens; Future directions; References; Chapter 6 Preparative regimens for lymphoma: allogeneic hematopoietic stem cell transplantation; Introduction; Myeloablative conditioning regimens for lymphomas

Reduced-intensity conditioning regimens RIC allo-HCT in diffuse large B-cell lymphoma; RIC allo-HCT for follicular lymphoma; RIC allo-HCT in mantle cell lymphoma; RIC allo-HCT in Hodgkin lymphoma; Incorporating monoclonal antibodies in preparative regimens for allo-HCT; Alternative donor sources; Umbilical cord blood cells; Haploidentical transplantation; Vaccine strategies in allo-HCT; Discussion and future direction; References; Chapter 7 Pretransplantation evaluation, comorbidities, and nondisease-related eligibility criteria for transplantation in lymphoma; Introduction; Initial steps

Preparation for transplant center evaluation

Notes:

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

9781118863275

1118863275

9781118863268

1118863267

9781118863282

1118863283

OCLC:

904012321