GERD : reflux to esophageal adenocarcinoma / Parakrama T. Chandrasoma, Tom DeMeester.

Format:

Book

Author/Creator:

Chandrasoma, Para.

Contributor:

DeMeester, Tom R., 1938-

Language:

English

Subjects (All):

Gastroesophageal reflux.

Esophagus--Cancer.

Esophagus.

Physical Description:

1 online resource (482 p.)

Edition:

1st ed.

Place of Publication:

Oxford : Academic, 2006.

Language Note:

English

Summary:

The increasing incidence of esophageal adenocarcinoma has created an enormous interest and stimulus for research in this area. GERD brings together, for the first time, a vast amount of disparate literature and documents the entire pathogenesis of reflux disease in one place. The book presents reflux carditis as a new diagnostic criterion of GERD and for the first time defines the dilated end-stage esophagus and the earliest microscopic phase of GERD that is missed by present diagnostic criteria. GERD presents both clinical and pathological information and is meant to be used as

Contents:

Front cover; Title page; Copyright page; Table of contents; Preface; CHAPTER 1: Overview of Gastroesophageal Reflux Disease; PHYSIOLOGICAL VERSUS PATHOLOGICAL REFLUX; PREVALENCE OF GASTROESOPHAGEAL REFLUX DISEASE; HISTOLOGIC DEFINITION OF GASTROESOPHAGEAL REFLUX DISEASE; PREVALENCE OF BARRETT ESOPHAGUS; MANAGEMENT OF BARRETT ESOPHAGUS; PREVALENCE OF REFLUX-INDUCED ADENOCARCINOMA; CHAPTER 2: The Past, Present, and Future of Columnar-Lined (Barrett) Esophagus; THE HISTORY OF COLUMNAR-LINED ESOPHAGUS; THE REASONS FOR CONFUSION; HISTORICAL EVOLUTION OF COLUMNAR-LINED (BARRETT) ESOPHAGUS

THE STATE OF THE ART AND TODAY'S PROBLEMSSOLUTIONS TO THE PROBLEM AND WHAT WE HOPE TO SHOW; CHAPTER 3: Fetal Development of the Esophagus and Stomach; THE STUDY OF EMBRYOLOGY OF THE FOREGUT; EARLY DEVELOPMENT OF THE GASTROINTESTINAL TRACT; EARLY DEVELOPMENT OF THE FOREGUT; EPITHELIAL DEVELOPMENT IN THE FETAL ESOPHAGUS; EPITHELIAL DEVELOPMENT IN THE FETAL STOMACH; EPITHELIAL DEVELOPMENT IN THE FETAL GASTROESOPHAGEAL JUNCTION; SUMMARY OF EPITHELIAL DEVELOPMENT OF THE ESOPHAGUS; CONTROL OF FOREGUT EPITHELIAL DEVELOPMENT; CHAPTER 4: Normal Anatomy

Present Definition of the Gastroesophageal JunctionANATOMY AND PHYSIOLOGY; ENDOSCOPIC/GROSS LANDMARKS; THE MEANING OF ENDOSCOPIC/GROSS LANDMARKS; PRESENT DEFINITION OF THE GASTROESOPHAGEAL JUNCTION; WHAT IS THE CARDIA? LET'S REMOVE THIS TERM FROM OUR VOCABULARY; THE LOGICAL CONCLUSION THAT SHOULD BE TESTED; CHAPTER 5: Histologic Definitions and Diagnosis of Epithelial Types; DEFINITIONS; PROBLEMS WITH THE DEFINITIONS; DIAGNOSIS OF DIFFERENT EPITHELIAL TYPES; CHAPTER 6: Cardiac Mucosa; WHAT IS CARDIAC MUCOSA?; WHERE IS CARDIAC MUCOSA LOCATED?; IS CARDIAC MUCOSA PRESENT IN EVERYONE?

WHAT IS OXYNTOCARDIAC MUCOSA, AND WHERE IS IT?HOW MUCH CARDIAC AND OXYNTOCARDIAC MUCOSA ARE PRESENT?; WHAT DOES THE PRESENCE/ABSENCE AND AMOUNT OF CARDIAC MUCOSA MEAN?; WHAT DOES INCREASING LENGTH OF CARDIAC MUCOSA MEAN?; A HUMAN EXPERIMENT; SUMMARY STATEMENT REGARDING CARDIAC MUCOSA; CHAPTER 7: New Histologic Definitions of Esophagus, Stomach, and Gastroesophageal Junction; LET US ESTABLISH COMMON GROUND IN HISTOLOGY; LET US UNDERSTAND THE PROBLEM; NORMAL HISTOLOGY OF THE ESOPHAGUS AND STOMACH: A STATEMENT OF FACT AND NEW HISTOLOGIC DEFINITIONS; APPLICATION OF THESE DEFINITIONS TO PRACTICE

CHAPTER 8: Pathology of Reflux Disease at a Cellular Level: Part 1-Damage to Squamous Epithelium and Transformation into Cardiac MucosaREFLUX-INDUCED DAMAGE OF THE SQUAMOUS EPITHELIUM; COLUMNAR METAPLASIA OF THE SQUAMOUS EPITHELIUM; SUMMARY; CHAPTER 9: The Pathology of Reflux Disease at a Cellular Level: Part 2-Evolution of Cardiac Mucosa to Oxyntocardiac Mucosa and Intestinal Metaplasia; HISTOLOGIC COMPOSITION OF COLUMNAR-LINED ESOPHAGUS; CARDIAC TO OXYNTOCARDIAC MUCOSA: THE BENIGN GENETIC SWITCH; CARDIAC MUCOSA TO INTESTINAL METAPLASIA: THE SECOND GENETIC SWITCH

CHAPTER 10: Pathology of Reflux Disease at a Cellular Level: Part 3-Intestinal (Barrett) Metaplasia to Carcinoma

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-4933-0073-3

1-280-63664-5

9786610636648

0-08-046474-2

OCLC:

469393376